{"id":497727,"date":"2026-06-17T18:36:10","date_gmt":"2026-06-17T18:36:10","guid":{"rendered":"https:\/\/www.newsbeep.com\/il\/497727\/"},"modified":"2026-06-17T18:36:10","modified_gmt":"2026-06-17T18:36:10","slug":"mayim-bialiks-nightmare-experience-with-single-dose-of-a-glp-1","status":"publish","type":"post","link":"https:\/\/www.newsbeep.com\/il\/497727\/","title":{"rendered":"Mayim Bialik&#8217;s \u2018Nightmare\u2019 Experience with Single Dose of a GLP-1"},"content":{"rendered":"<p><img decoding=\"async\" loading=\"eager\" src=\"https:\/\/www.newsbeep.com\/il\/wp-content\/uploads\/2026\/06\/Mayim_Bialik_GLP-1-header-1296x728-1.jpg\" alt=\"Mayim Bialik at a ceremony\" class=\"css-bt1qz0\"\/><a class=\"icon-hl-pinterest css-foz1gx\" target=\"_blank\" rel=\"noopener noreferrer nofollow\" data-event=\"Any Page|Image Pinterest Click|Icon Clicked\" data-element-event=\"OPEN|CONTENTBLOCK|Any Page|Article Body|BUTTON|Image Widget Pinterest Click|\" href=\"https:\/\/www.pinterest.com\/pin\/create\/button\/?url=https%3A%2F%2Fwww.healthline.com%2Fhealth-news%2Fmayim-bialik-nightmare-glp-1-experience&amp;media=https%3A%2F%2Fmedia.post.rvohealth.io%2Fwp-content%2Fuploads%2F2026%2F06%2FMayim_Bialik_GLP-1-header-1296x728-1.jpg&amp;description=Mayim%20Bialik&#039;s%20%E2%80%98Nightmare%E2%80%99%20Experience%20with%20Single%20Dose%20of%20a%20GLP-1\" title=\"Share on Pinterest\" data-pin-custom=\"true\" data-share-url=\"https:\/\/www.newsbeep.com\/il\/wp-content\/uploads\/2026\/06\/Mayim_Bialik_GLP-1-header-1296x728-1.jpg\">Share on Pinterest<\/a>Mayim Bialik recently shared the \u201cnightmare\u201d experience she had after using a GLP-1 drug. Image Credit: Laurent Koffel\/Getty ImagesActor Mayim Bialik has shared her \u201cnightmare\u201d experience that left her with weeks of side effects after one GLP-1 medication dose. Bialik said her symptoms included severe diarrhea and full-body aches. She revealed that she tried a GLP-1 after her doctor suggested it may help with her autoimmune disease symptoms.<\/p>\n<p>Emmy Award-winning actor Mayim Bialik, of \u201cBlossom\u201d and \u201cBig Bang Theory\u201d fame, opened up about her experience with a GLP-1 medication. <\/p>\n<p>In an essay for <a href=\"https:\/\/www.thefp.com\/p\/mayim-bialik-glp1-side-effects\" target=\"_blank\" rel=\"noopener noreferrer nofollow\" class=\"content-link css-kxhged\">The Free Press<\/a>, Bialik wrote, \u201cTo say I had an adverse reaction would be somewhat of an understatement.\u201d <\/p>\n<p>After one low dose injection of the <a href=\"https:\/\/www.healthline.com\/health\/weight-loss\/glp1-for-weight-loss\" class=\"content-link css-kxhged\" rel=\"nofollow noopener\" target=\"_blank\">GLP-1 medication<\/a>, she said she began to experience gastrointestinal symptoms that left her unwell for weeks. <\/p>\n<p>When Bialik visited a gastroenterologist about her symptoms, she was told that dramatic side effects from GLP-1 drugs can be quite common. The doctor also informed Bialik that the other medications she was taking may have contributed to her symptoms. <\/p>\n<p>Here\u2019s why Bialik turned to GLP-1s and why her autoimmune disease symptoms may have exacerbated her side effects.<\/p>\n<p>Bialik shared that she had gained around 20 pounds during early <a href=\"https:\/\/www.healthline.com\/health\/menopause\" class=\"content-link css-kxhged\" rel=\"nofollow noopener\" target=\"_blank\">menopause<\/a>. <\/p>\n<p>However, that wasn\u2019t why she started using a GLP-1 medication. She had been told that the medication may help ease some of the symptoms she had lived with most of her adult life. <\/p>\n<p>At 48, Bialik consulted with various specialists for other symptoms she was experiencing after <a href=\"https:\/\/www.healthline.com\/health\/menopause\/difference-perimenopause\" class=\"content-link css-kxhged\" rel=\"nofollow noopener\" target=\"_blank\">perimenopause<\/a>. Each physician gave her a separate <a href=\"https:\/\/www.healthline.com\/health\/autoimmune-disorders\" class=\"content-link css-kxhged\" rel=\"nofollow noopener\" target=\"_blank\">autoimmune<\/a> diagnosis, but none seemed 100% certain.<\/p>\n<p>She decided to try a GLP-1, not for her postmenopause weight gain, but because three separate doctors suggested she try it to help with her autoimmune symptoms. There is evidence to show GLP-1s may help reduce inflammation. <\/p>\n<p>However, after one dose of the GLP-1 medication, Bialik began to experience severe side effects. <\/p>\n<p>She wrote in her <a href=\"https:\/\/www.thefp.com\/p\/mayim-bialik-glp1-side-effects\" target=\"_blank\" rel=\"noopener noreferrer nofollow\" class=\"content-link css-kxhged\">essay<\/a> that she experienced \u201cexplosive, uncontrollable diarrhea. Sulfur burps so violent, they left me afraid to open my mouth in public. Sneezing attacks every time I tried to eat or drink\u2014which apparently has a name: <a href=\"https:\/\/www.healthline.com\/health\/sneezing-after-eating\" class=\"content-link css-kxhged\" rel=\"nofollow noopener\" target=\"_blank\">snatiation<\/a>.\u201d <\/p>\n<p>\u201cCramping. Bloating. Full-body aching, as though I had the flu,\u201d she said. <\/p>\n<p>\u201cAnd an inability to keep down even small sips of water without sprinting to the bathroom with yet more explosive diarrhea. More than three times, I didn\u2019t make it.\u201d <\/p>\n<p><a href=\"https:\/\/www.jlplasticsurgery.com\/\" target=\"_blank\" rel=\"noopener noreferrer nofollow\" class=\"content-link css-kxhged\">Jeffrey Lee<\/a>, MD, a double board certified plastic surgeon and founder of JL Plastic Surgery in Boston, MA, told Healthline in a <a href=\"https:\/\/www.healthline.com\/health-news\/hidden-side-effects-glp-1-drugs-ozempic-reddit-study\" target=\"_blank\" rel=\"noreferrer noopener nofollow\" class=\"content-link css-kxhged\">previous interview<\/a> that gastrointestinal side effects from GLP-1s are not unusual.<\/p>\n<p>\u201cThe most common side effects I see in practice are gastrointestinal, things like nausea, bloating, or constipation,\u201d Lee said.<\/p>\n<p>Bialik said that although her GLP-1 experience was a \u201cnightmare,\u201d it shouldn\u2019t overshadow the widespread success that millions of people have had with this class of drugs.<\/p>\n<p>\u201cGLP-1s have helped people in serious need,\u201d Bialik said. \u201cOf that I am certain. But nobody talks much about what happens when it goes wrong.\u201d<\/p>\n","protected":false},"excerpt":{"rendered":"Share on PinterestMayim Bialik recently shared the \u201cnightmare\u201d experience she had after using a GLP-1 drug. Image Credit:&hellip;\n","protected":false},"author":2,"featured_media":497728,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[33],"tags":[163,85,46,482],"class_list":["post-497727","post","type-post","status-publish","format-standard","has-post-thumbnail","category-medication","tag-health","tag-il","tag-israel","tag-medication"],"_links":{"self":[{"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/posts\/497727","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/comments?post=497727"}],"version-history":[{"count":0,"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/posts\/497727\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/media\/497728"}],"wp:attachment":[{"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/media?parent=497727"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/categories?post=497727"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/tags?post=497727"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}