Intracranial aneurysms are weakened, bulging areas of cerebral arteries that can rupture,\u00a0causing\u00a0subarachnoid\u00a0hemorrhage\u00a0and, in turn, significant\u00a0disability or\u00a0death.\u00a0While endovascular treatments have advanced significantly, wide-necked\u00a0intracranial\u00a0aneurysms\u00a0present major\u00a0challenges,\u00a0as\u00a0coils\u00a0may move\u00a0the parent artery\u00a0during embolization.\u00a0In such cases, stent-assisted coiling,\u00a0which\u00a0places a scaffold across the neck to stabilize\u00a0coils,\u00a0can be\u00a0useful.\u00a0One such device, the\u00a0low-profile visualized intraluminal support\u00a0(LVIS)\u00a0stent,\u00a0is\u00a0a braided,\u00a0self-expanding nitinol device with\u00a0relatively high\u00a0metal coverage. Beyond providing scaffolding, it\u00a0may also alter blood flow inside the aneurysm and encourage thrombosis and healing.\u00a0However, a thorough evaluation of its safety profile is still lacking.\u00a0<\/p>\n
Addressing this challenge, a research team led by Professor Xiang Xu from the Department of Neurosurgery at the Tangshan\u00a0Gongren\u00a0Hospital,\u00a0China, evaluated whether LVIS stent-assisted coiling could provide effective aneurysm occlusion while producing measurable hemodynamic changes and\u00a0maintaining\u00a0procedural safety. The retrospective study included 61 patients\u00a0with wide-necked intracranial aneurysms receiving LVIS stent-assisted coiling\u00a0between January and December 2023: 35 had ruptured aneurysms and 26 had unruptured aneurysms. Researchers assessed immediate angiographic occlusion using the Raymond-Roy Occlusion Classification (RROC), functional outcomes using the modified Rankin Scale (mRS), follow-up angiography, parent artery patency, recurrence, and complications. A subset of 14 patients underwent computational fluid dynamics (CFD) analysis before treatment, after treatment, and at 6 months. This paper was published in Volume 12 of the\u00a0Chinese Neurosurgical Journal\u00a0on June 29, 2026.\u00a0<\/p>\n
Initial angiography showed complete occlusion (RROC class I) in 28 of 35 ruptured aneurysms (80%) and 22 of 26 unruptured aneurysms (84.6%). Angiographic follow-up was available for 27 patients (44.3%) at 6\u201312 months. All aneurysms initially completely occluded remained stably occluded, while some class II aneurysms improved to complete occlusion. In ruptured cases,\u00a0favorable\u00a0outcomes (mRS\u00a00\u20131) increased from 57.1% at discharge to 77.1% at 3\u20136 months. Among unruptured cases, 25 of 26 patients (96.2%) had\u00a0mRS\u00a00\u20131 at discharge, and all surviving patients\u00a0maintained\u00a0favorable\u00a0outcomes at follow-up.\u00a0<\/p>\n
CFD analysis showed that treatment reduced blood-flow activity within the aneurysm. In 14 patients, the amount of blood entering the aneurysm decreased after treatment, as did the proportion of the aneurysm exposed to higher flow and the average force exerted by blood on the vessel wall. These improvements\u00a0remained\u00a0significantly different from baseline at 6 months, with all\u00a0P\u00a0< 0.001.\u00a0<\/p>\n
“The sustained reduction in intra-aneurysmal flow parameters suggests that LVIS-assisted coiling can produce durable hemodynamic\u00a0remodeling,” Prof.\u00a0Xu noted, while emphasizing that the findings are observational rather than proof of causation.\u00a0<\/p>\n
The study also highlights procedural risks. Two patients with ruptured aneurysms experienced intraprocedural thrombosis and were successfully treated without permanent neurological deficits. Incomplete stent apposition was\u00a0observed\u00a0in 6 of 61 patients (9.8%). One patient with an unruptured aneurysm developed delayed in-stent thrombosis and died after unsuccessful rescue treatment and secondary cerebral\u00a0hemorrhage, resulting in an overall procedure-related mortality of 1.6%.\u00a0<\/p>\n
<\/p>\n
These findings underscore the importance of stent deployment and attention to thrombotic risk.”\u00a0<\/p>\n
\n
<\/p>\n
Professor Xiang Xu, Department of Neurosurgery, Tangshan Gongren Hospital, China<\/p>\n
<\/p>\n
The findings support collaboration among neurointerventional, imaging, and computational researchers to evaluate stent apposition and thrombotic risk prospectively to improve patient selection.\u00a0<\/p>\n
Overall, the findings suggest that LVIS stent-assisted coiling may combine mechanical support with flow modification for wide-necked intracranial aneurysms, while underscoring risks of stent thrombosis and incomplete apposition. Because the study was retrospective, single-center, clinically heterogeneous, and had a 44.3% angiographic follow-up rate, the authors caution against causal conclusions. Larger prospective, comparative studies will be needed to\u00a0establish\u00a0safety, efficacy<\/a>, and the potential role of this approach across ruptured and unruptured aneurysms.\u00a0<\/p>\n Source:<\/p>\n Chinese Neurosurgical Journal<\/a><\/p>\n Journal reference:<\/p>\n Dong, B., et al. (2026)\u00a0Safety and hemodynamic efficacy of the LVIS stent in the endovascular treatment of intracranial wide-necked aneurysms: a single-center retrospective study. Chinese Neurosurgical Journal. DOI: 10.1186\/s41016-026-00435-9.\u00a0https:\/\/link.springer.com\/article\/10.1186\/s41016-026-00435-9<\/a>\u00a0<\/p>\n","protected":false},"excerpt":{"rendered":"Intracranial aneurysms are weakened, bulging areas of cerebral arteries that can rupture,\u00a0causing\u00a0subarachnoid\u00a0hemorrhage\u00a0and, in turn, significant\u00a0disability or\u00a0death.\u00a0While endovascular treatments…\n","protected":false},"author":2,"featured_media":66914,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[10],"tags":[48372,85941,4208,164,3393,9937,163,4144,85,46,32600,8262,1360,79516,6210,125,100259],"class_list":["post-581630","post","type-post","status-publish","format-standard","has-post-thumbnail","category-health","tag-aneurysm","tag-angiography","tag-blood","tag-brain","tag-disability","tag-efficacy","tag-health","tag-hospital","tag-il","tag-israel","tag-neck","tag-neurosurgery","tag-research","tag-stent","tag-stress","tag-technology","tag-thrombosis"],"_links":{"self":[{"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/posts\/581630","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/comments?post=581630"}],"version-history":[{"count":0,"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/posts\/581630\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/media\/66914"}],"wp:attachment":[{"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/media?parent=581630"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/categories?post=581630"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/tags?post=581630"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}