Computers in Biology and Medicine<\/a>.<\/p>\nPatients in intensive care often experience high degrees of fluctuation in their blood pressure. If it\u2019s too high, that can lead to stroke, heart attacks, and kidney damage. Too low might mean not enough blood getting to the brain and vital organs.<\/p>\n
The current standard for continuously monitoring blood pressure is an arterial line\u2014a catheter inserted directly into an artery, typically in the arm or the groin, that provides continuous, real-time pressure tracking. The procedure works very well, but comes with a high risk of bleeding, clotting, and infection. It also limits mobility.<\/p>\n
Familiar blood pressure cuffs that wrap around the arm aren\u2019t invasive, but they only provide intermittent readings. The team created a system called MOSAIC based on two sensors\u2014one placed on a patient\u2019s chest, and the other on a finger. Together the sensors record the heart\u2019s electrical activity and the flow of blood through the body and relay these signals to a deep learning model that generates a waveform, a continuous readout of blood pressure over time.<\/p>\n
\u201cWe reconstruct waveform data in a way that\u2019s meaningful, accurate, reliable and, most importantly, non-invasive,\u201d says senior author Robert Stevens, chief of the Division of Informatics, Integration, and Innovation at Johns Hopkins Medicine.<\/p>\n
\u201cIt\u2019s a possible solution for avoiding the current standard of care for measuring blood pressure, arterial lines, a very invasive procedure with a risk of many complications.\u201d<\/p>\n
In an initial study of 28 patients in the intensive care unit at Johns Hopkins Hospital, the system generated waveforms that closely matched those recorded by traditional arterial catheters.<\/p>\n
\u201cWe\u2019re very close to hitting that gold standard,\u201d Harris says. \u201cThis demonstrates we can do what we set out to do\u2014and pretty well.\u201d<\/p>\n
The team is now validating the sensors and algorithm in a larger cohort of Johns Hopkins ICU patients.<\/p>\n
Longer term, the researchers hope the system could reduce the need for invasive monitoring and become a way to continuously measure blood pressure in a range of settings\u2014in regular hospital wards and at home.<\/p>\n
The team envisions people who have hypertension, one of the most common and the deadliest diseases worldwide, could wear the sensors daily to keep an eye on their blood pressure. They hope the sensors could bring about a paradigm change for the millions of people living with hypertension, the way glucose monitors have for people with diabetes.<\/p>\n
The sensors could also be used on healthy people to gain insights into daily blood pressure fluctuations and trends during daily activities.<\/p>\n
\u201cWe observe sick patients in the intensive care unit, but we have no idea what\u2019s going on with blood pressure in a healthy person who\u2019s just living their life, going to work and being with their family,\u201d Stevens says. \u201cWhat happens to their blood pressure day after day? Nobody really knows.\u201d<\/p>\n
The work was supported by the Johns Hopkins Institute for Clinical and Translational Research, through the National Institutes of Health\u2019s National Center for Advancing Translational Sciences, NIH Roadmap for Medical Research, and a National Science Foundation Graduate Research Fellowship.<\/p>\n
Source: Johns Hopkins University<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"Share this Article You are free to share this article under the Attribution 4.0 International license. Wearable sensors…\n","protected":false},"author":2,"featured_media":591901,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[10],"tags":[343,3554,163,85,46,3381],"class_list":["post-591900","post","type-post","status-publish","format-standard","has-post-thumbnail","category-health","tag-artificial-intelligence","tag-blood-pressure","tag-health","tag-il","tag-israel","tag-wearable-devices"],"_links":{"self":[{"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/posts\/591900","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/comments?post=591900"}],"version-history":[{"count":0,"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/posts\/591900\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/media\/591901"}],"wp:attachment":[{"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/media?parent=591900"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/categories?post=591900"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/tags?post=591900"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}