Understanding how bacteria influence each other is essential if we want to predict or eventually manipulate microbiome composition in a rational way<\/p>\n
Andr\u00e9 Mateus<\/p>\n
The results showed that most interactions were negative, meaning that one species limited the growth of another. A major reason was that bacteria altered their environment, particularly by changing its pH, making it more acid. \u201dOur results show that competition is a dominant feature of the gut microbiome. At the same time, we found specific examples of cooperation and identified the molecular mechanisms behind them,\u201d says Bolor Buyanbadrakh, Postdoctoral Fellow at the Department of Chemistry at Ume\u00e5 University and first author of the study.\u00a0<\/p>\n
One finding was that Clostridium perfringens promotes the growth of Mediterraneibacter gnavus through the release of extracellular vesicles, tiny particles released by bacteria that can carry molecules between cells. The study provides evidence that such vesicles can directly influence the growth of another bacterial species.\u00a0<\/p>\n
The researchers also discovered that Veillonella parvula can increase the pH of its surroundings, counteracting acidification caused by other bacteria. This change allowed acid-sensitive species, such as Parabacteroides merdae, to grow more effectively, even in more complex microbial communities.\u00a0<\/p>\n
\u201dUnderstanding how bacteria influence each other is essential if we want to predict or eventually manipulate microbiome composition in a rational way. Our work provides both a large interaction dataset and mechanistic insights that move the field in that direction,\u201d says Andr\u00e9 Mateus, assistant professor at the Department of Chemistry and senior author of the study.\u00a0<\/p>\n
Source: Ume\u00e5 University\u00a0<\/p>\n","protected":false},"excerpt":{"rendered":"Understanding how bacteria influence each other is essential if we want to predict or eventually manipulate microbiome composition…\n","protected":false},"author":2,"featured_media":601348,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[10],"tags":[271878,163,85,46],"class_list":["post-601347","post","type-post","status-publish","format-standard","has-post-thumbnail","category-health","tag-umeauniv-brumeauniversitet-bsky-social","tag-health","tag-il","tag-israel"],"_links":{"self":[{"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/posts\/601347","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/comments?post=601347"}],"version-history":[{"count":0,"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/posts\/601347\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/media\/601348"}],"wp:attachment":[{"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/media?parent=601347"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/categories?post=601347"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/tags?post=601347"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}