NOCTURIA and urgency urinary incontinence (UUI) were associated with distinct systemic health patterns in US men aged 40 years and older,\u00a0according to new evidence.\u00a0<\/p>\n
These findings come from an analysis of 11,236 participants across seven survey cycles conducted between 2005\u00a0and\u00a02018, with mortality follow-up through 2019.\u00a0<\/p>\n
Researchers classified participants into four mutually exclusive groups: neither symptom, nocturia only\u00a0(25.6%), UUI only\u00a0(3.2%), and both symptoms\u00a0(5.1%).\u00a0<\/p>\n
Nocturia and Cardiometabolic Health\u00a0<\/p>\n
Analysis revealed that symptom composition provided\u00a0important information\u00a0beyond symptom count alone.\u00a0\u00a0<\/p>\n
Men with\u00a0nocturia<\/a>\u00a0only were more likely to have advanced\u00a0cardiovascular kidney metabolic<\/a>\u00a0status compared with those without symptoms.\u00a0\u00a0<\/p>\n In contrast, coexisting nocturia and UUI were strongly associated with poor cardiovascular health.\u00a0<\/p>\n UUI alone did not\u00a0demonstrate\u00a0a dominant cardiovascular kidney metabolic or cardiovascular health pattern.\u00a0<\/p>\n Researchers found that the two single symptom groups were\u00a0generally similar\u00a0across broader health outcomes, suggesting that symptom composition only influenced selected systemic associations.\u00a0<\/p>\n Symptom Burden Increases with Symptom Number\u00a0<\/p>\n The study also\u00a0demonstrated\u00a0a stepwise increase in health burden as symptom number rose from zero to one and then two symptoms.\u00a0\u00a0<\/p>\n Compared with men without symptoms, those with two symptoms had markedly higher odds of severe functional limitation,\u00a0depressive symptoms,\u00a0and\u00a0all-cause\u00a0mortality.\u00a0<\/p>\n Men with both symptoms also experienced greater burden than either single symptom group, including higher rates of multimorbidity, sleep problems,\u00a0self-reported\u00a0poor health, and mortality.\u00a0\u00a0<\/p>\n Polypharmacy was more common among symptomatic participants but did not differ clearly between the coexisting symptom group and single symptom groups.\u00a0<\/p>\n Clinical Implications for Assessment\u00a0<\/p>\n The authors concluded that a simple classification based on nocturia and UUI may help clinicians\u00a0identify\u00a0broader systemic vulnerability.\u00a0\u00a0<\/p>\n Symptom count\u00a0appeared to reflect\u00a0the overall breadth of health burden, while symptom composition highlighted specific areas for investigation.\u00a0<\/p>\n The findings suggest that patients with both symptoms may\u00a0benefit\u00a0from comprehensive evaluation of physical function, mood, sleep, comorbidity burden, and medication use.\u00a0\u00a0<\/p>\n Meanwhile, nocturia alone may\u00a0warrant\u00a0closer assessment of cardiovascular kidney metabolic health,\u00a0whereas\u00a0coexisting symptoms may\u00a0indicate\u00a0a need to examine overall cardiovascular health more closely.\u00a0<\/p>\n Reference\u00a0<\/p>\n Yu J\u00a0et al. Systemic health patterns associated with nocturia and urgency urinary incontinence in US men. Sci Rep.\u00a02026;DOI:10.1038\/s41598-026-70522-5.\u00a0<\/p>\n Featured\u00a0image:\u00a0Satjawat\u00a0on Adobe Stock<\/p>\n","protected":false},"excerpt":{"rendered":"NOCTURIA and urgency urinary incontinence (UUI) were associated with distinct systemic health patterns in US men aged 40…\n","protected":false},"author":2,"featured_media":616747,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[10],"tags":[163,85,46],"class_list":["post-616746","post","type-post","status-publish","format-standard","has-post-thumbnail","category-health","tag-health","tag-il","tag-israel"],"_links":{"self":[{"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/posts\/616746","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/comments?post=616746"}],"version-history":[{"count":0,"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/posts\/616746\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/media\/616747"}],"wp:attachment":[{"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/media?parent=616746"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/categories?post=616746"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/tags?post=616746"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}