{"id":660747,"date":"2026-10-29T15:34:10","date_gmt":"2026-10-29T15:34:10","guid":{"rendered":"https:\/\/www.newsbeep.com\/il\/660747\/"},"modified":"2026-10-29T15:34:10","modified_gmt":"2026-10-29T15:34:10","slug":"study-of-100000-australians-seeks-causes-of-mental-health-disorders-and-early-onset-cancer-health","status":"publish","type":"post","link":"https:\/\/www.newsbeep.com\/il\/660747\/","title":{"rendered":"Study of 100,000 Australians seeks causes of mental health disorders and early onset cancer | Health"},"content":{"rendered":"<p class=\"dcr-1s160rg\">Researchers hope to better understand the drivers of major health challenges facing younger people, such as mental illness and rising cancer rates, through the recruitment of 100,000 people for Australia\u2019s largest intergenerational study of wellbeing and ageing.<\/p>\n<p class=\"dcr-1s160rg\">The independent and not-for-profit research institute the Sax Institute, on Thursday launched the 18 and Up study, which will follow the health of those aged 18 to 45 throughout their lives.<\/p>\n<p class=\"dcr-1s160rg\">Two decades ago, the institute started 45 and Up, now the largest population-based cohort study in the southern hemisphere, with more than 267,000 participants ranging in age from 45 to older than 100.<\/p>\n<p class=\"dcr-1s160rg\">Since then, participants have been repeatedly surveyed and their responses linked to other datasets, leading to significant discoveries <a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC4339244\/\" data-link-name=\"in body link\" rel=\"nofollow noopener\" target=\"_blank\">about smoking<\/a>, <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/39875685\/\" data-link-name=\"in body link\" rel=\"nofollow noopener\" target=\"_blank\">dementia prevention<\/a>, and <a href=\"https:\/\/www.saxinstitute.org.au\/news\/gender-makes-a-difference-in-preventive-treatment-after-heart-attack\/\" data-link-name=\"in body link\" rel=\"nofollow noopener\" target=\"_blank\">differences in cardiovascular outcomes<\/a> between men and women.<\/p>\n<p><a data-link-name=\"standard link button Primary\" data-spacefinder-role=\"inline\" data-ignore=\"global-link-styling\" href=\"https:\/\/www.theguardian.com\/email-newsletters?CMP=copyembed&amp;CMP=emailbutton\" class=\"dcr-rh233e\" rel=\"nofollow noopener\" target=\"_blank\">Sign up for the Breaking News Australia email<\/a><\/p>\n<p class=\"dcr-1s160rg\">18 and Up\u2019s scientific director, Adjunct Prof Justine Gatt, said there was a lack of long-term data for younger generations, with existing studies often only giving researchers information from a snapshot in time.<\/p>\n<p class=\"dcr-1s160rg\">\u201cAlmost two in five young Australians aged 16 to 24 experienced a mental disorder in the past year, and that number has been rising,\u201d Gatt, a neuroscientist and mental health researcher said. \u201cYet we still lack the long-term evidence needed to understand why.\u201d<\/p>\n<p class=\"dcr-1s160rg\">Suicide is the leading cause of death among Australians aged 15 to 44, and researchers have said there is an urgent need to <a href=\"https:\/\/www.theguardian.com\/society\/article\/2024\/aug\/14\/alarming-surge-in-mental-ill-health-among-young-people-in-face-of-unprecedented-challenges-experts-warn\" data-link-name=\"in body link\" rel=\"nofollow noopener\" target=\"_blank\">understand and address driving factors<\/a> to improve prevention efforts and mental health treatments.<\/p>\n<p class=\"dcr-1s160rg\">Children and grandchildren of 45 and Up participants will be invited to participate, which Gatt said will help researchers understand how health is influenced by a complex mix of family history, lived experiences and social conditions, and how these factors interact across generations.<\/p>\n<p class=\"dcr-1s160rg\">The CEO of the Sax Institute, Dr Martin McNamara, said along with mental health, questions around cancer will also be an important part of the initial round of surveys.<\/p>\n<p>\u2018It\u2019s important we follow people over time \u2026 so that we can figure out ways to fix and re-organise our health and care systems,\u2019 says Sax Institute CEO Dr Martin McNamara. Photograph: SAX Institute<\/p>\n<p class=\"dcr-1s160rg\">Since 2000, <a href=\"https:\/\/www.theguardian.com\/australia-news\/2023\/aug\/02\/too-young-why-are-australians-under-50-increasingly-being-diagnosed-with-cancer\" data-link-name=\"in body link\" rel=\"nofollow noopener\" target=\"_blank\">there has been an increase in early-onset cancers<\/a> \u2013 defined as those diagnosed beyond adolescence but before the age of 50 \u2013 in Australia and other parts of the world. This <a href=\"https:\/\/www.canceraustralia.gov.au\/cancer-types\/early-onset-cancer\" data-link-name=\"in body link\" rel=\"nofollow noopener\" target=\"_blank\">includes bowel, thyroid, breast<\/a> and other cancers.<\/p>\n<p class=\"dcr-1s160rg\">While scientists think increased screening, changing lifestyles and different exposures to risk factors in early life and young adulthood may all be factors, there have been calls for <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC9406462\" data-link-name=\"in body link\" rel=\"nofollow noopener\" target=\"_blank\">urgent research<\/a> to better understand these and other influences.<\/p>\n<p class=\"dcr-1s160rg\">Participants will be asked about health, lifestyle, social circumstances and background and, with consent, this information will be linked to other health records, such as cancer registries and Medicare.<\/p>\n<p class=\"dcr-1s160rg\">\u201cIt\u2019s important we follow people over time \u2026 so that we can figure out ways to fix and re-organise our health and care systems,\u201d McNamara said.<\/p>\n<p><a data-ignore=\"global-link-styling\" href=\"#EmailSignup-skip-link-16\" class=\"dcr-76akua\">skip past newsletter promotion<\/a>Free newsletter |When needed<\/p>\n<p class=\"dcr-vf9hps\">Sign up to Breaking News Australia<\/p>\n<p class=\"dcr-djbwnz\">Get the most important news as it breaks<\/p>\n<p><img src=\"https:\/\/www.newsbeep.com\/il\/wp-content\/uploads\/2026\/10\/1793288050_892_2998.jpg\" alt=\"\" loading=\"lazy\" decoding=\"async\" class=\"dcr-gx9601\"\/><\/p>\n<p id=\"EmailSignup-skip-link-16\" tabindex=\"0\" aria-label=\"after newsletter promotion\" role=\"note\" class=\"dcr-76akua\">after newsletter promotion<\/p>\n<p class=\"dcr-1s160rg\">\u201cWe\u2019ll have a really good picture of their lives, the things that are important to them, their education, their employment, where they live.\u201d<\/p>\n<p class=\"dcr-1s160rg\">The study will evolve with participants to receive age-relevant questions, and emerging health conditions or pandemics will be factored in. It is being funded by a $4.5m National <a href=\"https:\/\/www.theguardian.com\/australia-news\/health\" data-link-name=\"in body link\" data-component=\"auto-linked-tag\" rel=\"nofollow noopener\" target=\"_blank\">Health<\/a> and Medical Research Council grant, with recruitment beginning in November.<\/p>\n<p class=\"dcr-1s160rg\">Professor of epidemiology and public health at the Australia National University, Emily Banks, is a former scientific director at the Sax Institute who used 45 and Up study data <a href=\"https:\/\/reporter.anu.edu.au\/all-stories\/australias-biggest-killer-smoking-causes-66-deaths-every-day-and-24000-a-year\" data-link-name=\"in body link\" rel=\"nofollow noopener\" target=\"_blank\">to reveal in 2025<\/a> that smoking-related illnesses kill 66 Australians every day \u2013 more than previously thought.<\/p>\n<p class=\"dcr-1s160rg\">Banks said large-scale cohort studies are powerful as they give researchers a window into the population and help detail what people are exposed to during their lives. She said the 45 and Up data has become an important collaborative resource.<\/p>\n<p class=\"dcr-1s160rg\">It <a href=\"https:\/\/www.saxinstitute.org.au\/solutions\/45-and-up-study\/use-the-45-and-up-study\/\" data-link-name=\"in body link\" rel=\"nofollow noopener\" target=\"_blank\">has been used by more than 800 researchers worldwide<\/a>.<\/p>\n<p class=\"dcr-1s160rg\">\u201cWe\u2019ve had hundreds of researchers using the data. We also have around 10% of the population of New South Wales in that age [45+] group in the study,\u201d she said.<\/p>\n<p class=\"dcr-1s160rg\">\u201cSome of the biggest advances in health have come from using this kind of information.\u201d<\/p>\n<p class=\"dcr-1s160rg\"> In Australia, support is available at <a href=\"https:\/\/www.beyondblue.org.au\/\" data-link-name=\"in body link\" rel=\"nofollow noopener\" target=\"_blank\">Beyond Blue<\/a> on 1300 22 4636, <a href=\"https:\/\/www.lifeline.org.au\/\" data-link-name=\"in body link\" rel=\"nofollow noopener\" target=\"_blank\">Lifeline<\/a> on 13 11 14 and at <a href=\"https:\/\/mensline.org.au\/\" data-link-name=\"in body link\" rel=\"nofollow noopener\" target=\"_blank\">MensLine<\/a> on 1300 789 978.<\/p>\n","protected":false},"excerpt":{"rendered":"Researchers hope to better understand the drivers of major health challenges facing younger people, such as mental illness&hellip;\n","protected":false},"author":2,"featured_media":660748,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[35],"tags":[163,85,46,522,523],"class_list":["post-660747","post","type-post","status-publish","format-standard","has-post-thumbnail","category-mental-health","tag-health","tag-il","tag-israel","tag-mental-health","tag-mentalhealth"],"_links":{"self":[{"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/posts\/660747","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/comments?post=660747"}],"version-history":[{"count":0,"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/posts\/660747\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/media\/660748"}],"wp:attachment":[{"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/media?parent=660747"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/categories?post=660747"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/tags?post=660747"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}