Helmed by H Vinoth, Jana Nayagan also stars Pooja Hegde, Bobby Deol, Priyamani, Prakash Raj, Gautham Vasudev Menon, Mamitha Baiju, and Narain. The film reunites Vijay with Prakash Raj after Varisu, Pooja after Beast, and Gautham Vasudev Menon after Leo.
On the technical side, the film has music by Anirudh, cinematography by Sathyan Sooryan, editing by Pradeep E Ragav, action choreography by Anl Arasu, and art direction by Selva Kumar.