Regulators are trying to push drug development into a post-animal testing era. Meanwhile, a Jennifer Doudna-founded company is edging toward successful CAR-T therapy done in vivo, and a “triple-G” drug from Eli Lilly delivers strong results.

Lastly, don’t forget that today is STAT’s Breakthrough Summit East! Virtual tickets still available.

In-vivo CAR-T inches toward clinical reality

A new Nature paper from Azalea Therapeutics, a spinout of Jennifer Doudna’s lab, offers an early but notable step toward in vivo CAR-T — engineering cancer-fighting T cells directly inside the body rather than through the laborious lab-driven process.

STAT+ Exclusive Story

STAT+



This article is exclusive to STAT+ subscribers
Unlock this article — plus in-depth analysis, newsletters, premium events, and news alerts.

Already have an account? Log in

Individual plans

Group plans

View All Plans

To read the rest of this story subscribe to STAT+.

Subscribe