Project approval was given more than 10 years ago, but building work did not start until 2021.
Construction – at the main Foresterhill campus in Aberdeen – has been hit by problems including issues with water and ventilation systems and design issues.
In March, BBC Scotland News revealed wall panels and insulation have had to be ripped out due to mould.
Infection control teams sounded the alarm after construction materials were allowed to get wet.
The Baird Family Hospital will offer maternity and breast-screening services, as well as a neonatal unit and operating theatre.
The Anchor Centre will bring together services including radiotherapy, oncology, haematology and research.
A report by project director Ian Matthewson will go before the NHS Grampian Board on Thursday.