Two fire trucks and an operational support unit attended the scene.
Hato Hone St John said they responded with three ambulances, a rapid response unit and a manager to the scene.
Two people were taken to Auckland City hospital in a serious condition.
Residents in the area came out of their homes to watch as emergency crews extracted a man from one vehicle. Debris and shattered glass were littered everywhere.
The vehicle sustained serious damage, while a bus involved in the crash further up the road also sustained moderate damage. Photo / Hayden Woodward
Authorities closed off part of Don Buck Rd as a result of the crash.
Police said they responded to reports of a crash on Don Buck Road at around 9:20pm.
“We can confirm that there are injuries.”