Credit: NBC

Luke Mitchell (Dr. Mitchell Ripley) – EXPECTED TO RETURN
The Blindspot actor first booked a recurring guest starring role in Season 9. He plays Dr. Mitch Ripley, an Emergency Department doctor with a troubled past who shares a history with Dr. Charles (Platt). He made his debut in the premiere episode of Season 9, and is expected back for Season 12.
As for whether Mitch Ripley/Caitlin Lenox enter the prion trial? “I do think that’s possible, yes. I think that this disclosure between them at the end of the season, she will have a more positive attitude moving into next season and will be wanting to embrace life in a healthier way. She thought she was embracing life this season, but she was really being self-destructive,” said the showrunner to Parade.

Sarah Ramos (E.D. Dr. Caitlin Lenox) – EXPECTED TO RETURN
Parenthood star Sarah Ramos joined as Dr. Caitlin Lenox in Season 10, and is expected back for Season 12.