Improving survival in people with severe psychiatric disorders
An expert editorial suggests that widely used diabetes and obesity drugs may help close the long-standing mortality gap…
Opioid receptor agonists take advantage of new understanding of GPCR biology
 Opioid receptors are fantastic targets for treating pain—but unfortunately, the drugs that target them can be addictive.…
Study finds GLP-1 drugs improve strength and reverse aging biology in mice
New multi-omic data reveal that GLP-1 signaling in the brain can drive body-wide rejuvenation, offering a potential weight-neutral…
New insight into TRPM3 heat sensor reveals how the body detects temperature
The ability to sense heat protects the body from burns and injury. But how the body actually feels…
GLP-1 therapeutics may have the potential to treat alcohol and drug addiction
A popular class of therapies for treating diabetes and obesity may also have the potential to treat alcohol…
Exercise found to reduce artery hardening after weight loss in adults with obesity
Maintaining weight loss with regular exercise rather than the glucagon-like peptide-1 receptor agonist (GLP-1RA) liraglutide, a drug used…