Study finds GLP-1 medicines cut fat while preserving muscle function
A new study in mice and humans suggests GLP-1 medicines drive weight loss primarily by reducing fat, while…
Investigating microglia’s role in Alzheimer’s pathology
Announcing a new article publication for BIO Integration journal. Alzheimer’s disease (AD) is a neurodegenerative disorder and the…
Combined GLP-1 and GLP-2 treatment appears safe but does not beat placebo for obesity
Can combining two gut hormone pathways unlock better obesity treatments? In the first human trial of dapiglutide, researchers…
UCLA Health finds eco-friendly inhalers improve COPD outcomes
New research from UCLA Health suggests that certain inhalers used to treat chronic obstructive pulmonary disease (COPD) are…
Improving survival in people with severe psychiatric disorders
An expert editorial suggests that widely used diabetes and obesity drugs may help close the long-standing mortality gap…
Opioid receptor agonists take advantage of new understanding of GPCR biology
 Opioid receptors are fantastic targets for treating pain—but unfortunately, the drugs that target them can be addictive.…
Study finds GLP-1 drugs improve strength and reverse aging biology in mice
New multi-omic data reveal that GLP-1 signaling in the brain can drive body-wide rejuvenation, offering a potential weight-neutral…
New insight into TRPM3 heat sensor reveals how the body detects temperature
The ability to sense heat protects the body from burns and injury. But how the body actually feels…
GLP-1 therapeutics may have the potential to treat alcohol and drug addiction
A popular class of therapies for treating diabetes and obesity may also have the potential to treat alcohol…
Exercise found to reduce artery hardening after weight loss in adults with obesity
Maintaining weight loss with regular exercise rather than the glucagon-like peptide-1 receptor agonist (GLP-1RA) liraglutide, a drug used…