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Browsing Tag

Allele

2 posts
HHealth
Study: APOE4 to APOE2 allelic switching in mice improves Alzheimer’s disease-related metabolic signatures, neuropathology and cognition. Image Credit: Lightspring / Shutterstock
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Switching APOE4 to APOE2 in adult mice reduces Alzheimer’s pathology and improves memory

  • November 12, 2025
By flipping a single genetic switch from APOE4 to APOE2 in adult mice, researchers reversed key Alzheimer’s-like changes…
HHealth
Study: Lymphoid gene expression supports neuroprotective microglia function. Image Credit: sfam_photo / Shutterstock
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Alzheimer’s breakthrough reveals how tweaking one gene shields brain connections

  • November 6, 2025
Scientists have uncovered a microglial switch that transforms these immune cells from plaque-promoting to plaque-protective, offering a new…
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