Targeted fab fragments dismantle the allergy trigger
Allergic diseases represent a major global health burden, placing significant strain on healthcare systems worldwide. Severe conditions such…
Epigenetic plasticity in germinal center B cells may help explain lymphoma origins
Immune cells called B cells make antibodies that fight off invading bacteria, viruses and other foreign substances. During…
Using sound waves to soften tumors and boost chemotherapy
Cancer is one of the leading causes of death in the U.S., second only to heart disease. But…
Early RSV infection turns maternal allergy into a powerful driver of childhood asthma
By combining nationwide health data with elegant immunology experiments, researchers reveal how RSV infection in infancy hijacks maternal…
Gene variant linked to higher risk of chronic rejection after lung transplant
About one third of lung transplant recipients have a genetic variant that makes them more likely to develop…
Breakthrough in FcγRI inhibition opens path to safer autoimmune therapies
An international research group directed by UMC Utrecht have developed and characterized two first-in-class antibodies that specifically block…
New antibody strategy shows promise for halting cyst growth in polycystic kidney disease
Polycystic kidney disease (PKD) is a debilitating hereditary condition in which fluid-filled sacs form and proliferate in the…
T cells drive vaccine effectiveness against porcine reproductive and respiratory syndrome virus
A new study shows that the effectiveness of current vaccines against porcine reproductive and respiratory syndrome virus (PRRSV)…
Study links common Epstein-Barr virus to autoimmune lupus
One of humanity’s most ubiquitous infectious pathogens bears the blame for the chronic autoimmune condition called systemic lupus…
Academic AIs make inroads in protein binder design
 Researchers from the University of Washington’s Institute for Protein Design have developed a new variation of diffusion-based…
Northwestern team develops antibody to expose hidden pancreatic cancer cells
Pancreatic cancer is notoriously hard to treat and often resists the most advanced immunotherapies. Northwestern Medicine scientists have…
Lactate and lactylation drive metabolic, epigenetic reprogramming in gynecological cancers
Lactate, once considered a metabolic waste product, is now recognized as a key regulator of cellular homeostasis and…