Targeted fab fragments dismantle the allergy trigger
Allergic diseases represent a major global health burden, placing significant strain on healthcare systems worldwide. Severe conditions such…
Customizable protein platforms offer new hope for cancer treatment
Precise methods for shredding or repairing and replacing specific cancer-causing proteins in a malignant cell, developed at the…
Researchers discover how Mycoplasma pneumoniae acquires cholesterol from human hosts
A multidisciplinary team has uncovered a key mechanism that allows the human bacterium Mycoplasma pneumoniae-responsible for atypical pneumonia…
Epigenetic plasticity in germinal center B cells may help explain lymphoma origins
Immune cells called B cells make antibodies that fight off invading bacteria, viruses and other foreign substances. During…
Dinutuximab beta plus chemotherapy shrinks neuroblastoma tumors in children
Children with a rare form of cancer called neuroblastoma which hasn’t responded to initial treatment or that has…
Novel antibody suppresses primary tumor growth and spread of triple-negative breast cancer
Triple-negative breast cancer (TNBC) is one of the most aggressive and treatment-resistant forms of breast cancer. It grows…
Calcium-activated switch improves delivery and potency of cancer-fighting drugs
Cancer-fighting antibody drugs are designed to penetrate tumor cells and release a lethal payload deep within, but too…
Breakthrough in FcγRI inhibition opens path to safer autoimmune therapies
An international research group directed by UMC Utrecht have developed and characterized two first-in-class antibodies that specifically block…
New antibody strategy shows promise for halting cyst growth in polycystic kidney disease
Polycystic kidney disease (PKD) is a debilitating hereditary condition in which fluid-filled sacs form and proliferate in the…
T cells drive vaccine effectiveness against porcine reproductive and respiratory syndrome virus
A new study shows that the effectiveness of current vaccines against porcine reproductive and respiratory syndrome virus (PRRSV)…
Northwestern team develops antibody to expose hidden pancreatic cancer cells
Pancreatic cancer is notoriously hard to treat and often resists the most advanced immunotherapies. Northwestern Medicine scientists have…
Low-cost biosensor identifies altered protein levels associated with psychiatric disorders
Brazilian researchers have developed a low-cost, portable biosensor that can quickly identify a protein whose altered levels are…