Study reveals how germinal centers consistently produce antibodies
A new study tracking thousands of B cells across more than 100 germinal centers in mice reveals how…
Researchers discover a biological barrier that limits mucosal vaccine immunity
A consistent biological barrier that stops the immune system from making the antibodies most needed to protect the…
Study finds serious blood-related side effects associated with antibody-drug conjugates
A major real-world study by University of California, Irvine pharmacy researchers has found serious blood-related side effects associated…
AI-based generative framework create all-atom models of proteins in motion
Many drug and antibody discovery pathways focus on intricately folded cell membrane proteins. When molecules of a drug…
Alzheimer’s monoclonal antibodies fail to deliver meaningful results
Despite successfully removing amyloid plaques from the brain, widely anticipated antibody therapies fail to deliver meaningful cognitive improvements,…
Engineered Stem Cells Become Lifelong Protein Factories
Researchers have genetically engineered blood stem cells to produce B cells that can churn out rare broad-action antibodies…
Study finds long COVID leaves a distinct immune signature in the blood
Blood tests revealed protein patterns tied to long COVID months after infection, while booster shots did not appear…
Study explains why vaccines underperform in people living with obesity
New findings reveal that obesity significantly impaired the quality and longevity of antibody responses to a Pseudomonas aeruginosa…
CAR T therapy induces remission in multiple autoimmune diseases
For the first time, scientists have used a cutting-edge cell therapy called CAR-T to treat a patient with three different life-threatening autoimmune diseases that…
Investigating microglia’s role in Alzheimer’s pathology
Announcing a new article publication for BIO Integration journal. Alzheimer’s disease (AD) is a neurodegenerative disorder and the…
New structural insights pave way for hantavirus vaccines
Hantaviruses, transmitted from rodents to people, have a death rate approaching 40%. They’re found around the world, and…
Remote-controlled CAR T cells offer safer cancer therapy
Among the most promising tools of cancer therapy, engineered immune cells known as chimeric antigen-receptor (CAR) T cells…