APC-deficient cancer cells rely on single enzyme for survival
A newly published study reports that APC-deficient cancer cells may depend on a single metabolic enzyme for survival,…
Blocking nitric oxide suppresses tumor growth in aggressive pediatric neuroblastoma
The tumor begins before birth. Somewhere in the developing fetus, neural crest cells that should have matured into…
CSF1R T567M mutation induces microglial dysfunction and synaptic impairment in patient iPSC-derived cerebral organoids of CSF1R-related disorder
Ayrignac X, Carra-Dalliere C, Codjia P, Mouzat K, Castelnovo G, Ellie E, et al. Evaluation of CSF1R-related adult…
Enzyme helps maintain retinal progenitor cells during eye development
The retina is a thin layer of neural tissue at the back of the eye that detects light…
TREM2 helps macrophages survive and repair radiation damaged skin
Recently, teams led by Prof. Yiming Zhang from Xinqiao Hospital, Army Medical University,Prof. Fazhi Qi from Zhongshan Hospital,…
Reframing the role of MCL1 in cancer signaling and metabolism
A study by the Mildred Scheel Early Career Center group led by Dr. Mohamed Elgendy at the TUD…
How diabetes medications may influence cancer risk and progression
Diabetes, particularly Type 2 Diabetes (T2DM), has been linked to an increased risk of various cancers, including liver,…
Nanoflower-treated stem cells deliver healthier mitochondria to stressed cells
By engineering nanomaterials that boost mitochondrial biogenesis, researchers show how stem cells can become powerful “mitochondrial biofactories,” offering…
Everyday PFAS exposure alters placental function in early pregnancy
By modelling real-world PFAS mixtures found in first-trimester placentas, researchers reveal how everyday chemical exposure can subtly rewire…
AR3-based optogenetic strategy shows high efficacy in inducing apoptosis and antitumor effects
One of the hallmarks of cancer cells is their ability to evade apoptosis, or programmed cell death, through…
Restoration of BAP1 activity via base editing suppresses anchorage-independent survival in kidney cancer | Cancer Cell International
Jensen DE, Proctor M, Marquis ST, Gardner HP, Ha SI, Chodosh LA, Ishov AM, Tommerup N, Vissing H,…
Preclinical study shows aged garlic extract improves memory and reduces anxiety
New findings show that aged garlic extract reshapes brain pathways tied to memory and emotion, revealing a promising…