Dengue virus infects memory B cells to evade immune defenses
Researchers at the University of Vermont Robert Larner, M.D. College of Medicine and Upstate Medical University in Syracuse,…
Memory B cells reveal how nasal vaccines could stop respiratory infections earlier
New insights into lung-resident memory B cells show why the next generation of vaccines may need to protect…
New HIV vaccine successfully generates broadly neutralizing antibodies in primates
A new HIV vaccine developed by La Jolla Institute for Immunology (LJI), Scripps Research scientists, and IAVI has…
New mRNA flu vaccine offers broader protection against influenza strains
A new study led by researchers at Washington University School of Medicine in St. Louis has found that…
Study reveals how germinal centers consistently produce antibodies
A new study tracking thousands of B cells across more than 100 germinal centers in mice reveals how…
Researchers discover a biological barrier that limits mucosal vaccine immunity
A consistent biological barrier that stops the immune system from making the antibodies most needed to protect the…
Study reveals how inflammation disrupts lymph node structure in lymphoma
In aggressive lymphomas, inflammatory messengers reprogram the “conductors” of the immune system, causing lymph nodes structure to collapse.…
Epigenetic plasticity in germinal center B cells may help explain lymphoma origins
Immune cells called B cells make antibodies that fight off invading bacteria, viruses and other foreign substances. During…
Serious side effects after CAR T cell therapy for multiple myeloma share a common immune root cause
Serious side effects, including neurotoxicity and intestinal inflammation, that appear weeks or months after patients receive CAR T…
Reprogramming camp for immune cells shows early promise for autoimmune diseases
Scientists are trying a revolutionary new approach to treat rheumatoid arthritis, multiple sclerosis, lupus and other devastating autoimmune…
Study links common Epstein-Barr virus to autoimmune lupus
One of humanity’s most ubiquitous infectious pathogens bears the blame for the chronic autoimmune condition called systemic lupus…