Genetic variants in 11 regions of human genome influence the gut microbiome
In two new studies on 28,000 individuals, researchers are able to show that genetic variants in 11 regions…
CRISPR gene-drive technology reverses antibiotic resistance in bacteria
Antibiotic resistance (AR) has steadily accelerated in recent years to become a global health crisis. As deadly bacteria…
Bacteria repurpose viral injection systems to target diverse cells
New study shows how bacteria adapted a virus-derived injection system to recognize and attach to many different types…
Chlamydia pneumoniae found in the eye may aggravate Alzheimer’s disease
Chlamydia pneumoniae—a common bacterium that causes pneumonia and sinus infections—can linger in the eye and brain for years…
Scientists uncover new mechanism initiating gene transcription
Scientists at IOCB Prague are uncovering new details of gene transcription. They have identified a previously unknown molecular…
How modern lifestyles reprogram the gut microbiome and shape disease risk
From jet lag and poor sleep to exercise and chronic stress, this review unpacks how everyday lifestyle factors…
Bacterial infections in patients with liver cirrhosis show rising prevalence and high mortality
Background and aims Bacterial infections (BIs) are common and severe complications in patients with liver cirrhosis, but global…
Researchers discover how Mycoplasma pneumoniae acquires cholesterol from human hosts
A multidisciplinary team has uncovered a key mechanism that allows the human bacterium Mycoplasma pneumoniae-responsible for atypical pneumonia…
A precise tool to halt viral protein production
Across all domains of life, immune defenses foil invading viruses by making it impossible for the viruses to…
Why some bacteria survive antibiotics and how to stop them
New study reveals that bacteria can survive antibiotic treatment through two fundamentally different “shutdown modes,” not just the…
Phages use small RNA to hijack bacterial cells and boost replication
As antibiotic-resistant infections rise and are projected to cause up to 10 million deaths per year by 2050,…
SIRT3 deficiency worsens eustachian tube dysfunction during middle-ear infection
Middle-ear infections caused by Gram-negative bacteria remain among the most common pediatric illnesses worldwide. When the eustachian tube-responsible…