Natural sex reversal imparts permanent compositional changes to the swamp eel gonadal microbiome | Microbiome
Fish maintenance and trial design The sourcing of swamp eel and the rearing procedures employed in this study…
ParaRef: a decontaminated reference database for parasite detection in ancient and modern metagenomic datasets | Genome Biology
Blake DP, Betson M. One health: parasites and beyond. Parasitology. 2017;144:1–6. PubMed Google Scholar Coulter JBS. Global importance…
iNOME-seq: in vivo simultaneous genome-wide mapping of chromatin accessibility, nucleosome positioning, DNA-binding protein sites, and DNA methylation in Arabidopsis | Genome Biology
Plant lines and growth conditions The plant lines used in this study were derived from A. thaliana wild-type…
MultiModalGraphics: an R package for graphical integration of multi-omics datasets | BMC Bioinformatics
MultiModalGraphics is an R/Bioconductor package that leverages object-oriented S4 classes to visualize multimodal biological data with embedded statistical…
Topology-aware functional similarity: integrating extended neighborhoods via exponential attenuation | BMC Bioinformatics
Experiment datasets This study systematically evaluates protein-protein interaction (PPI) networks from four model organisms: Saccharomyces cerevisiae, Arabidopsis thaliana,…
World Record Set For Fastest Genome Sequencing | Health
Key Takeaways Researchers have set a new world record for fastest whole human genome sequencing The team completed…
Twenty years of genome-wide association studies: Health translation challenges and AI opportunities
Southam L, Zeggini E. Twenty years of genome-wide association studies. Nature. 2025;641:47–9. Article PubMed CAS Google Scholar Klein…
World Record Set For Fastest Genome Sequencing | Health
Key Takeaways Researchers have set a new world record for fastest whole human genome sequencing The team completed…
SPAmix: a scalable, accurate, and universal analysis framework for large-scale genetic association studies in admixed populations | Genome Biology
Model residuals of linear regression and logistic regression Linear regression and logistic regression are regular models to fit…
SAGPEK: fast and flexible approach to identify genotypes of Sanger sequencing data | BMC Bioinformatics
Software architecture SAGPEK mainly processes Sanger sequencing results of two kinds of samples: diploids such as humans and…
A novel gene expression stability metric to unveil homeostasis and regulation | Genome Biology
K-proportion and gene homeostasis Z-Index identify regulatory genes As cells of the same type and in the same…
Incorporating additive genetic effects and linkage disequilibrium information to discover gene-environment interactions using BV-LDER-GE | Genome Biology
Model overview We consider the following model to incorporate both additive and interaction effects: $${Y}_{i}={\sum }_{j=1}^{M}{G}_{ji}{\beta }_{j}+{\sum }_{j=1}^{M}{S}_{ji}{\gamma…