World Record Set For Fastest Genome Sequencing | Health
Key Takeaways Researchers have set a new world record for fastest whole human genome sequencing The team completed…
Twenty years of genome-wide association studies: Health translation challenges and AI opportunities
Southam L, Zeggini E. Twenty years of genome-wide association studies. Nature. 2025;641:47–9. Article PubMed CAS Google Scholar Klein…
World Record Set For Fastest Genome Sequencing | Health
Key Takeaways Researchers have set a new world record for fastest whole human genome sequencing The team completed…
SPAmix: a scalable, accurate, and universal analysis framework for large-scale genetic association studies in admixed populations | Genome Biology
Model residuals of linear regression and logistic regression Linear regression and logistic regression are regular models to fit…
SAGPEK: fast and flexible approach to identify genotypes of Sanger sequencing data | BMC Bioinformatics
Software architecture SAGPEK mainly processes Sanger sequencing results of two kinds of samples: diploids such as humans and…
A novel gene expression stability metric to unveil homeostasis and regulation | Genome Biology
K-proportion and gene homeostasis Z-Index identify regulatory genes As cells of the same type and in the same…
Incorporating additive genetic effects and linkage disequilibrium information to discover gene-environment interactions using BV-LDER-GE | Genome Biology
Model overview We consider the following model to incorporate both additive and interaction effects: $${Y}_{i}={\sum }_{j=1}^{M}{G}_{ji}{\beta }_{j}+{\sum }_{j=1}^{M}{S}_{ji}{\gamma…
TrueSpot: a robust automated tool for quantifying signal puncta in fluorescent imaging | Genome Biology
TrueSpot uses an automated threshold selection algorithm that utilizes multiple approaches TrueSpot accepts either a 2D image or…
From gut to gamete: how the microbiome influences fertility and preconception health | Microbiome
Inhorn MC, Patrizio P. Infertility around the globe: new thinking on gender, reproductive technologies and global movements in…
Advances in haplotype phasing and genotype imputation
Voight, B. F., Kudaravalli, S., Wen, X. & Pritchard, J. K. A map of recent positive selection in…
Genomenon and Compass Bioinformatics Partner to Transform Genomic Diagnostics in the U.S. and Japan
Mastermind® FLEX Data powers Compass Bioinformatics’s InheriNext® platform, bringing unparalleled genomic evidence to leading institutes across US, Japan,…
Fueling chromosomal gene diversification and artificial evolution with CRISPR | Genome Biology
Wilson DS, Keefe AD. Random mutagenesis by PCR. Curr Protoc Mol Biol. 2001;51:8–3. Google Scholar Reetz MT, Wu…