Health system learning enables generalist neuroimaging models
Health system learning We define ‘health system learning’ as learning directly from uncurated data generated during routine clinical…
The PRECISE European initiative for cancer-vulnerability mapping and prediction
Evangelia Petsalaki Present address: Oncology Data Science, GSK, Stevenage, UK These authors contributed equally: Francesco Iorio, Mathew J.…
Non-coding DNA dynamics and its roles as a physical barrier in genome safeguarding across early development and evolution
Aburomia R, Khaner O, Sidow A (2003) Functional evolution in the ancestral lineage of vertebrates or when genomic…
How parents decide whether to have genomic newborn screening: experiences from BabyScreen+
ParticipantsParticipation in BabyScreen+ and gNBS A total of 1139 participants consented to BabyScreen+ research, regardless of whether they…
Generative AI-enabled clinical decision support system in primary care: a pragmatic, cluster-randomized trial
Design We conducted a pragmatic, multicenter, parallel-group cluster-randomized controlled trial across a network of 16 primary care facilities…
Evaluating the robustness and readiness of large frontier models in health AI applications
Singhal, K. et al. Large language models encode clinical knowledge. Nature 620, 172–180 (2023). Article CAS PubMed PubMed…
Large reasoning models as thinking machines for medicine
Jaech, A. et al. OpenAI o1 system card. Preprint at https://arxiv.org/abs/2412.16720 (2024). Guo, D. et al. DeepSeek-R1 incentivizes…
General-purpose chatbots outperform clinical AI tools on physicians’ real-world questions
Publisher’s note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. This…
Implications of wait times for sentinel node biopsy on melanoma disease progression, micrometastatic tumour burden and survival outcomes in the modern treatment era
The data confirms that our service began to struggle to achieve a waiting time of 90 days or…
Advancing ferroptosis-targeted therapies
RESEARCH HIGHLIGHT 10 June 2026 ]]> Ferroptosis is a form of regulated cell death characterised by iron accumulation…
Medically tailored meals receipt and healthcare utilization and costs in Massachusetts’ Medicaid demonstration
Study design and setting We used a propensity score weighted, difference-in-difference analysis of adult MassHealth members with one…
The promise of adaptive health in the United Arab Emirates and beyond
Department of Medicine, Johns Hopkins University, Baltimore, MD, USA Andrew P. Feinberg Department of Biomedical Engineering, Johns Hopkins…