When helpfulness backfires: LLMs and the risk of false medical information due to sycophantic behavior
To evaluate language models across varying levels of drug familiarity, we used the RABBITS30 dataset, which includes 550…
Selection for somatic escape variants in SERPINA1 in the liver of patients with alpha-1 antitrypsin deficiency
Liver samples All liver samples were collected with written informed consent from Addenbrooke’s Hospital, Cambridge, UK, according to…
Meta-analysis reveals differences in somatic alterations by genetic ancestry across common cancers
Genetic ancestry is a quantitative measure of inherited genetic variation and correlates with human migration patterns1. It contributes…
Association between triglyceride-glucose index and pathological invasiveness of lung adenocarcinoma in patients with solitary ground-glass nodules: a cross-sectional study | BMC Cancer
In this retrospective analysis of 278 individuals with solitary pGGNs pathologically verified as lung adenocarcinoma following surgery, an…
Prevalence and factors associated with high-risk human papillomavirus infection and cervical lesions among women with HIV in Addis Ababa, Ethiopia | BMC Cancer
This study assessed the prevalence of hrHPV infection, the hrHPV genotype distribution, cervical lesions and associated factors in…
Population-scale gene-based analysis of whole-genome sequencing provides insights into metabolic health
Ethics Our research complies with all relevant ethical regulations. All studies included in this research were approved by…
Nucleotide dependency analysis of genomic language models detects functional elements
SpeciesLM training For SpeciesLM metazoa, we obtained metazoan genomes comprising 494 different species from the Ensembl 110 database36.…
Systematic review: digital biomarkers of fatigue in chronic diseases
The search yielded 845 papers; after removing duplicates, 570 papers were screened by title and abstract. leaving 88…
The surgical effect of inferior mesenteric artery ligation level in rectal cancer and sigmoid colon cancer: a meta-analysis of randomized controlled trials | BMC Cancer
Sung H, Ferlay J, Siegel RL, Laversanne M, Soerjomataram I, Jemal A, et al. Global cancer statistics 2020:…
α-L-fucosidase isoenzymes (FUCA1/FUCA2) as prognostic markers in gliomas: a comprehensive study | BMC Cancer
Clinical samples and ethics of study Sample acquisition: (1) Glioma tissues: 30 cases (25 grade II/III, 5 GBM;…
A genetic map of human metabolism across the allele frequency spectrum
Study design The UKB is a prospective cohort study from the UK that contains more than 500,000 volunteers…
Operationalizing machine-assisted translation in healthcare
Rawal, S. et al. Association between limited English proficiency and revisits and readmissions after hospitalization for patients with…