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Browsing Tag

Biomedicine

74 posts
HHealth
Development and external validation of a FISH-clinical nomogram for predicting overall survival in bladder cancer patients after radical cystectomy | BMC Cancer
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Development and external validation of a FISH-clinical nomogram for predicting overall survival in bladder cancer patients after radical cystectomy | BMC Cancer

  • October 25, 2025
Siegel RL, Miller KD, Wagle NS, Jemal A. Cancer statistics, 2023. CA Cancer J Clin. 2023;73(1):17–48. PubMed  Google…
GGenetics
The MyCancerGene study: a hybrid type 1 effectiveness-implementation randomized study comparing a patient-centered digital genetic health portal to usual care after receipt of cancer genetic testing | BMC Cancer
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The MyCancerGene study: a hybrid type 1 effectiveness-implementation randomized study comparing a patient-centered digital genetic health portal to usual care after receipt of cancer genetic testing | BMC Cancer

  • October 24, 2025
Robson ME, Storm CD, Weitzel J, Wollins DS, Offit K. American society of clinical oncology policy statement update:…
GGenetics
Pathogenic UNC13A variants cause a neurodevelopmental syndrome by impairing synaptic function
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Pathogenic UNC13A variants cause a neurodevelopmental syndrome by impairing synaptic function

  • October 23, 2025
Institute of Medical Genetics, University of Zurich, Zurich, Switzerland Reza Asadollahi, Paranchai Boonsawat, Dennis Kraemer & Anita Rauch Faculty of Engineering and…
GGenetics
Modeling heterogeneity in single-cell perturbation states enhances detection of response eQTLs
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Modeling heterogeneity in single-cell perturbation states enhances detection of response eQTLs

  • October 21, 2025
Cohorts We used published data (GEO accession no. GSE162632) to study the effect of 12 h of ex vivo…
GGenetics
Twenty years of genome-wide association studies: Health translation challenges and AI opportunities
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Twenty years of genome-wide association studies: Health translation challenges and AI opportunities

  • October 20, 2025
Southam L, Zeggini E. Twenty years of genome-wide association studies. Nature. 2025;641:47–9. Article  PubMed  CAS  Google Scholar  Klein…
GGenetics
Association of genetic variants in m1A modification core genes and neuroblastoma risk | BMC Cancer
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Association of genetic variants in m1A modification core genes and neuroblastoma risk | BMC Cancer

  • October 18, 2025
Park JR, Kreissman SG, London WB, Naranjo A, Cohn SL, Hogarty MD, et al. Effect of tandem autologous…
GGenetics
Redefining cellular reprogramming with advanced genomic technologies
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Redefining cellular reprogramming with advanced genomic technologies

  • October 18, 2025
Briggs, R. & King, T. J. Transplantation of living nuclei from blastula cells into enucleated Frogs’ eggs. Proc.…
HHealth
Curcumin in prostate cancer: a systematic review of molecular mechanisms and nanoformulated therapeutic strategies | BMC Cancer
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Curcumin in prostate cancer: a systematic review of molecular mechanisms and nanoformulated therapeutic strategies | BMC Cancer

  • October 18, 2025
Curcumin, a dietary polyphenol derived from Curcuma longa, has been extensively studied for its pleiotropic biological activities, particularly…
GGenetics
Characterization of induced cohesin loop extrusion trajectories in living cells
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Characterization of induced cohesin loop extrusion trajectories in living cells

  • October 18, 2025
Experiments performed in this study did not require ethics board approval. Cell culture HAP1 cells were cultured in…
HHealthcare
When helpfulness backfires: LLMs and the risk of false medical information due to sycophantic behavior
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When helpfulness backfires: LLMs and the risk of false medical information due to sycophantic behavior

  • October 17, 2025
To evaluate language models across varying levels of drug familiarity, we used the RABBITS30 dataset, which includes 550…
GGenetics
Selection for somatic escape variants in SERPINA1 in the liver of patients with alpha-1 antitrypsin deficiency
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Selection for somatic escape variants in SERPINA1 in the liver of patients with alpha-1 antitrypsin deficiency

  • October 17, 2025
Liver samples All liver samples were collected with written informed consent from Addenbrooke’s Hospital, Cambridge, UK, according to…
GGenetics
Meta-analysis reveals differences in somatic alterations by genetic ancestry across common cancers
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Meta-analysis reveals differences in somatic alterations by genetic ancestry across common cancers

  • October 17, 2025
Genetic ancestry is a quantitative measure of inherited genetic variation and correlates with human migration patterns1. It contributes…
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