Unstable immune cells linked to severe cancer immunotherapy side effects
Scientists at the University of Pittsburgh uncovered the unstable immune cells that can cause up to 40% of…
Study explains why cancer immunity declines faster in males
Lutz Menzel, PhD, formerly of the Department of Radiation Oncology within the Mass General Brigham Cancer Institute, and…
Study uncovers hidden switch that helps cancer cells to evade immune detection
Researchers from the Cancer Science Institute of Singapore (CSI Singapore) at the National University of Singapore (NUS) have…
New ultrasound technique breaches blood brain barrier to treat gliomas
In a promising sign for the potential of focused sound waves to improve care for brain tumors, UVA…
New strategy combines cancer immunotherapy and gene therapy in a single nanoparticle
Cancer cells survive by hiding from the immune system’s surveillance. A KAIST research team has developed a new…
Mass-producible immune cells fight solid human tumors in mice
Off-the-shelf and mass-producible immune cells fight solid human tumors engrafted into mice. The Kobe University development is a…
New biological feedback loop helps the immune system attack colorectal cancers
A subset of cancers, known as microsatellite instability (MSI) and deficient DNA mismatch repair (dMMR) cancers, are more…
New breast cancer classification system predicts immunotherapy response success
The advent of immune checkpoint inhibitors (ICIs) has marked a paradigm shift in cancer treatment, yet a significant…
Engineered silica nanoparticles destroy prostate tumors in preclinical study
Prostate-targeted, engineered nanoparticles made of amorphous silica are effective in killing prostate tumors directly while enhancing anti-tumor immunity,…
Targeting microRNA pathway helps overcome cancer immunotherapy resistance
Immune checkpoint therapy, a type of cancer immunotherapy that helps the immune system recognize and attack tumors, has…
Researchers develop pH and redox-sensitive systems to reduce immunotherapy toxicity
Although cancer immunotherapy has transformed treatment by harnessing the immune system to eliminate tumors, only a small subset…
New insights highlight multifaceted roles of CD4+ T cells in tumor immunity
For decades, cancer immunotherapy has focused primarily on CD8+ cytotoxic T lymphocytes as the main executors of tumor…