Genomic landscape and clinicopathologic significance of POLE mutant colorectal carcinoma
Background and objectives DNA polymerase epsilon catalytic subunit A (POLE) gene plays a crucial role in DNA repair…
Researchers develop new score to predict the risk of liver cancer
Researchers led by Xian-Yang Qin at the RIKEN Center for Integrative Medical Sciences (IMS) in Japan have developed…
University of Missouri launches first on-campus radiopharmaceutical clinical trial
In a major leap for cancer care at the University of Missouri, the School of Medicine and MU…
Genetic ancestry influences tumor biology and survival in head and neck cancers
Genetic ancestry plays a key role in determining the behavior of head and neck tumors and may help…
Antibiotics Up Risk for Skin Events in Cancer Immunotherapy
TOPLINE: In a retrospective cohort study, patients who used antibiotics during immune checkpoint blockade (ICB) therapy had an…
New NIH grants fuel research in oral cancer treatment and pain relief
Researchers at the School of Dentistry at UT Health San Antonio, the academic health center of The University…
Single-cell analysis reveals HPV-induced keratinocyte heterogeneity in cervical cancer
Cervical squamous cell carcinoma (CESC), the most prevalent subtype of cervical cancer, remains a major global health burden…
Researchers engineer a tool to dismantle cancer’s RNA-built growth hubs
In a city, coworking hubs bring people and ideas together. Inside cancer cells, similar hubs form-but instead of…
Genetic risk score can help identify women at higher risk of invasive breast cancer
Studying a person’s genetic makeup can predict if they will go on to develop invasive breast cancer after…
Study identifies key molecular and clinical biomarkers for MASLD
Background and aims The causal biomarkers for metabolic dysfunction-associated steatotic liver disease (MASLD) and their clinical value remain…
Loss of Trp53 gene affects immune responses in ovarian cancer
A new research paper was published in Volume 16 of Oncotarget on September 22, 2025, titled “Loss of Trp53 results in…
Coffee protects the liver by blocking inflammation and scarring, review finds
Scientists reveal how your daily cup of coffee may guard against liver disease, connecting population trends with the…