Base editing technique reveals crucial gene for early human development
Research led by the University of Cambridge Loke Centre for Trophoblast Research has shown that a genome editing…
New SMArT platform improves safety of CRISPR gene editing
A team of researchers led by Luigi Naldini at the San Raffaele Telethon Institute for Gene Therapy (SR-Tiget)…
Scientists develop safer CRISPR technique using gentler DNA nicking approach
Researchers at Cornell University have developed a safer and more precise way to study how genes function in…
Methylation-sensitive Cas9 can selectively target DNA in tumor cells
CRISPR-Cas gene-editing tools have revolutionized the world of biotechnology and medicine. And each year, it seems, these…
A safer gene-editing tool shows promise for transthyretin amyloidosis treatment
Genetic disorders occur due to alterations in the primary genetic material, deoxyribonucleic acid (DNA), of an organism. Transthyretin…
A precise tool to halt viral protein production
Across all domains of life, immune defenses foil invading viruses by making it impossible for the viruses to…
One-time CRISPR therapy safely lowers cholesterol and triglycerides in early trial
In a 15-patient, Phase 1 one, first-in-human trial, a one-time, CRISPR-Cas9 gene-editing therapy safely reduced LDL cholesterol and…
Study reveals acidic conditions as key to pancreatic cancer survival
Tumors are not a comfortable place to live: oxygen deficiency, nutrient scarcity, and the accumulation of sometimes harmful…