New insights highlight multifaceted roles of CD4+ T cells in tumor immunity
For decades, cancer immunotherapy has focused primarily on CD8+ cytotoxic T lymphocytes as the main executors of tumor…
Alzheimer’s plaques decline after CAR-T immune cell treatment in preclinical study
A novel CAR-T cell approach targets amyloid plaques in preclinical Alzheimer models, raising the possibility that engineered immune…
Immune system dysfunction may fuel progressive heart failure after heart attacks
When the heart’s muscle is weakened or injured due to a heart attack, it can make it hard…
Engineered extracellular vesicles enable antigen-specific regulatory T cell induction
A research team at the Nano Life Science Institute (WPI-NanoLSI) and the Faculty of Medicine at Kanazawa University…
Serious side effects after CAR T cell therapy for multiple myeloma share a common immune root cause
Serious side effects, including neurotoxicity and intestinal inflammation, that appear weeks or months after patients receive CAR T…
Single-cell RNA sequencing uncovers diverse CD4⁺ T-cell subtypes in pediatric lupus
Detailed mapping of CD4⁺ T cells from children with systemic lupus erythematosus (SLE) has revealed distinct immune cell…
New clues in pancreas lymph nodes, spleen could help detect and prevent type 1 diabetes
Type 1 diabetes (T1D) impacts nearly two million Americans, and by the time most people learn they have…
Common food additives may trigger childhood asthma
A recent study published in Frontiers in Immunology utilized metabolomics to investigate the mechanisms underlying the association between food…