Serious side effects after CAR T cell therapy for multiple myeloma share a common immune root cause
Serious side effects, including neurotoxicity and intestinal inflammation, that appear weeks or months after patients receive CAR T…
Study finds no specific harms linked to hydroxyurea exposure during pregnancy
Taking the sickle cell drug hydroxyurea during or shortly before pregnancy does not appear to cause specific issues…
New evidence shows hematopoietic cell transplantation offers durable relief for sickle cell disease
Patients who underwent hematopoietic cell transplantation for sickle cell disease saw high rates of survival without disease symptoms…
Novel antibody suppresses primary tumor growth and spread of triple-negative breast cancer
Triple-negative breast cancer (TNBC) is one of the most aggressive and treatment-resistant forms of breast cancer. It grows…
Study shines light on how P2X4 receptor can be inhibited
A study carried out by the University of Bonn and the University Hospital Bonn throws light on how…
Early pregnancy placenta models show significant effects from PFAS exposure
Per- and polyfluoroalkyl substances (PFAS) are a group of nearly 10,000 long-lasting chemical compounds that stay in the…
Retinal organoids provide a powerful tool to diagnose and study Leber congenital amaurosis
Leber Congenital Amaurosis (LCA) is an inherited retinal disease leading to severe vision impairment from early infancy, affecting…
Experimental RNA drug shows promise for repairing DNA and healing tissue damage
Cedars-Sinai scientists have developed an experimental drug that repairs DNA and serves as a prototype for a new…
New method reveals how human cells initiate DNA replication
When cells proliferate, genomic DNA is precisely duplicated once per cell cycle. Abnormalities in this DNA replication process…
How tick saliva reprograms the skin’s immune defenses
A research team led by the Medical University of Vienna has gained new insights into how ticks influence…
AR3-based optogenetic strategy shows high efficacy in inducing apoptosis and antitumor effects
One of the hallmarks of cancer cells is their ability to evade apoptosis, or programmed cell death, through…
New technique overcomes technological barrier in 3D brain imaging
Scientists at the Swiss Light Source SLS have succeeded in mapping a piece of brain tissue in 3D…