New breast cancer classification system predicts immunotherapy response success
The advent of immune checkpoint inhibitors (ICIs) has marked a paradigm shift in cancer treatment, yet a significant…
Experimental drug shields nerve cells from damage caused by ALS
Amyotrophic Lateral Sclerosis, or ALS, received widespread awareness in the summer of 2014 thanks to an Ice Bucket…
Vascular organoids may be an effective treatment for ischemic heart disease
Ischemic heart disease (IHD), also known as coronary artery disease, is a leading cause of death and morbidity…
Evolutionary noncoding RNAs reveal new targets for cancer therapy
In cancer research, one person’s junk is increasingly becoming another person’s treasure. Scientists have now uncovered new evidence…
Study potential new therapeutic strategy for patients with ATRX-mutant gliomas
A new study from researchers at The University of Texas MD Anderson Cancer Center has uncovered how one of…
Scientists map how chronic stress alters somatostatin levels in the brain
Consider the brake. Not the engine, which gets all the attention, but the brake, the quiet thing that…
New structural insights overturn old assumptions about malaria entry
For nearly half a century, scientists have known that malaria parasites force their way into human red blood cells through a…
Review links iron-dependent cell death to pathogenesis of Friedreich’s Ataxia
Published in the open-access journal Ferroptosis and Oxidative Stress, the review by Giovanni Cravin and Giorgio Cozza from the University of…
Genetic research links KDF1 mutation to impaired dental epithelial organization
Dental enamel is the hardest substance in the human body, protecting teeth from wear, temperature changes, and decay.…
Smoking reprograms immune cells to accelerate cardiovascular disease
Scientists at the University of Oklahoma have identified a previously unrecognized immune system pathway that helps explain how…
New drug candidate reduces toxic protein clumps of Huntington’s disease
An experimental drug has been shown to alleviate symptoms of Huntington’s disease and extend lifespan in mouse models.…
New schistosomiasis vaccine induces robust immune memory responses
For a vaccine to be effective, it must do two things. First, it must trigger an immune response.…