APC-deficient cancer cells rely on single enzyme for survival
A newly published study reports that APC-deficient cancer cells may depend on a single metabolic enzyme for survival,…
Targeting glutamine metabolism enhances CAR-macrophage cancer therapy
Tumor-associated macrophages (TAMs) within the tumor microenvironment (TME) exhibit significant metabolic dysregulation, which impairs their antitumor function. Specifically,…
Fermentation boosts anti-inflammatory power in dairy alternatives
Fermented plant-based dairy alternatives may do more than improve taste. This study reveals how they reshape bioactive lipids…
New study reveals CRISPR enzyme that responds to human DNA methylation
Cancer cells excel at evading detection, but subtle chemical differences set them apart from healthy cells. Now, a…
Researchers discover how cell membrane composition drives cancer proliferation
Cells are enveloped by a lipid membrane that gives them structure and provides a barrier between the cell…
Scientists find unexpected immune pathways for mRNA cancer vaccines
The advent of mRNA vaccines against SARS-CoV-2 in 2020 changed the course of the COVID-19 pandemic. Now, the…
High-resolution study maps molecular differences across six human cortical regions
A new analysis of individual brain cells across several human brain regions reveals subtle but widespread differences in…
Researchers use tiny glass capillaries to sample living cancer cell parts
A new analytical method could improve how cancer treatments are designed – by allowing scientists to track, for…
How the immune system may influence Alzheimer’s, Parkinson’s, and related diseases
A sweeping review shows how the brain’s immune defenses can both fight and fuel neurodegeneration, revealing why timing,…
Understanding cell messaging provides a blueprint for targeting inaccessible tumors
Researchers at University College Dublin have discovered a previously unknown “courier system” that cells use to deliver coherent…
Epigenetic changes allow cancer cells to shift identity and survive drugs
Cancer drugs are designed to shut tumors down. But sometimes, in the very act of attacking a tumor,…
Central Hawke’s Bay mum has leg removed in fight against clear cell sarcoma pain
When Hawke’s Bay Today spoke with her in June last year, she was fundraising to travel and get…