Study reveals a new facet of how pancreatic cancer cells regulate autophagy
A feature of pancreatic cancer cells’ surroundings determines whether they grow fast or become resistant to chemotherapy, a…
Chronic inflammation shapes cancer progression and immunotherapy response
Chronic inflammation is both a driver and suppressor of cancer depending on context. Key players-NF-κB, IL-6, STAT3, TAMs,…
Senescent astrocytes identified as key drivers of Alzheimer’s progression
Researchers from the NeuroAD group (Neuropathology of Alzheimer’s Disease) within the Department of Cell Biology, Genetics and Physiology…
Global study reveals disparities in early-onset gastric cancer
Gastric cancer remains the fifth leading cause of cancer-related deaths worldwide. Although its overall incidence has declined, early-onset…
Nasal COVID vaccine boost increases IgA responses linked to variant neutralisation
A novel nasal booster approach may help close the gap between systemic vaccination and infection-blocking mucosal immunity, offering…
Vitamin A and thyroid hormones in the retina shape fetal vision
Humans develop sharp vision during early fetal development thanks to an interplay between a vitamin A derivative and thyroid…
Study reveals insights into how cells coordinate gene compensation response
Some genetic mutations that are expected to completely stop a gene from working surprisingly cause only mild or…
FDA-approved anti-seizure drug could help fight Alzheimer’s disease
While physicians and scientists have long known Alzheimer’s disease involves the buildup of toxic protein fragments in the…
Neuron lattice structure may guard against neurodegeneration
Brain cells are constantly swallowing material from the fluid that surrounds them – signaling molecules, nutrients, even pieces of their own surfaces – in a process…
Alzheimer’s plaques decline after CAR-T immune cell treatment in preclinical study
A novel CAR-T cell approach targets amyloid plaques in preclinical Alzheimer models, raising the possibility that engineered immune…
Tiny organism offers insight into neurological side effects of chemotherapy
Chemotherapy remains one of the most powerful tools in the fight against cancer, yet it often comes with…
Transcription factor HOXD13 drives melanoma growth and immune evasion
A molecule that helps regulate gene activity has also been shown to drive skin cancer growth and tumors’…