New CRISPR technique boosts mitochondrial function to treat heart failure
After a heart attack, the heart struggles to recoup and maintain energy. One third of patients develop heart…
FOXJ3 gene identified as the critical link between abnormal brain development and epilepsy
Researchers have discovered that mutations in the FOXJ3 gene act as a “master switch” failure, disrupting how the…
Understanding PIEZO2 mutations and sensory disorders
Every time we feel a gentle tap on the skin, specialized nerve cells convert that physical force into…
Unmasking the hyper-active circuitry of early Alzheimer’s
Neuroscientists at King’s College London have pinpointed a mechanism behind the increased neural connectivity observed in the very early stages of Alzheimer’s…
How somatic mutations shape disease and reveal new drug targets
Scientists reveal how evolution within our own tissues can drive disease, protect cells, and uncover hidden therapeutic targets…
Scientists identify common molecular program across multiple brain tumor types
Research uncovering the origin of pineoblastoma, a rare pediatric brain tumor, has also revealed a dependency across multiple…
Research spotlights microbiota modulation by protein source
Whey protein isolate was associated with an increase in Bacteroidetes, while pea protein and mixed plant protein correlated…
New microscope captures 3D blood flow and oxygenation at single-cell resolution
The brain relies on real-time delivery of oxygen and nutrients through its microvasculature, which threads through neural tissue…
Study reveals a disease-relevant role for tanycytes in neurodegeneration
Accumulation of the protein tau in the brain is one of the hallmarks of Alzheimer’s disease. In a paper publishing March…
Targeted mRNA delivery restores sperm production and fertility in infertile mice
Researchers have found that targeted delivery of messenger RNA (mRNA) can restore sperm production and fertility in genetically…
Long COVID taste loss tied to reduced expression of key taste genes
Even after the virus disappears, some people continue to experience altered taste. New research suggests that subtle molecular…
New fragmentome technology can detect early liver fibrosis and cirrhosis
Researchers at the Johns Hopkins Kimmel Cancer Center report that an artificial intelligence (AI)-based liquid biopsy test using genome-wide cell-free…