Thiostrepton suppresses rhabdomyosarcoma progression by targeting the PI3K–AKT pathway
Rhabdomyosarcoma (RMS) accounts for up to 10% of childhood cancers and nearly half of pediatric soft tissue sarcomas.…
Two microbial metabolites compete to control the cells’ protein building machinery
The microbiome-the trillions of bacteria, viruses, and fungi that live quietly in our body-plays a crucial role in…
Understanding the role of m6A methylation in acute lung injury pathogenesis
Acute lung injury (ALI) is a critical clinical condition characterized by diffuse inflammation of the lung parenchyma and…
Scripps Research professor wins $3.2 million grant to unravel the mysteries of type 1 diabetes
Luc Teyton, professor in the Department of Immunology and Microbiology at Scripps Research, has received a five-year, $3.2…
Unlocking the secrets of NMDA receptors for better brain health
As information zings from cell to cell inside the brain, bursts of electricity spur its transmission. At Cold…
Experimental compound reduces cell death, inflammation, and organ damage in diabetes
An experimental compound reduced the cell death, inflammation, and organ damage seen with diabetes. Led by NYU Langone…
New biofilm discovery may pave way to undermining antibiotic-resistant Pseudomonas
The bacterium known as Pseudomonas aeruginosa is an unwelcome visitor in the human body. Serious infections can result…
Exploring the gut-brain-immune axis in neurodegeneration
Neurodegenerative diseases (NDs), such as Alzheimer’s disease (AD), Parkinson’s disease (PD), amyotrophic lateral sclerosis (ALS), and multiple sclerosis…
Using AI and citizen science for vector-borne disease surveillance
Researchers from the University of South Florida have used artificial intelligence and citizen science to identify what may…
Eating peanuts while pregnant may influence how a child’s genes respond to breastfeeding
Researchers found that mothers who ate both peanuts and peanut butter during pregnancy had children with distinct DNA…
Breakthrough study identifies potential treatment for schizophrenia symptoms
Difficulty completing everyday tasks. Failing memory. Unusually poor concentration. For many people living with schizophrenia, cognitive challenges are…
New insight into TRPM3 heat sensor reveals how the body detects temperature
The ability to sense heat protects the body from burns and injury. But how the body actually feels…