Single-cell sequencing reveals why some CAR-T therapies succeed while others fail
By mapping CAR-T cells one by one, researchers are uncovering the cellular traits that may separate durable cancer…
Simplified nanoparticles “educate” the immune system to find and destroy disease-causing cells
Johns Hopkins Medicine scientists say they have developed a simplified version of biodegradable nanoparticles that can “educate” the…
Chronic inflammation shapes cancer progression and immunotherapy response
Chronic inflammation is both a driver and suppressor of cancer depending on context. Key players-NF-κB, IL-6, STAT3, TAMs,…
Alzheimer’s plaques decline after CAR-T immune cell treatment in preclinical study
A novel CAR-T cell approach targets amyloid plaques in preclinical Alzheimer models, raising the possibility that engineered immune…
Silica nanomatrix enhances immunotherapy for solid tumors
Cancer has long remained a leading cause of death worldwide and in Hong Kong, accounting for 30% of…
Genetic modification enhances “living drugs” for blood cancers
CAR T cells are patient-derived, genetically engineered immune cells. They are “living drugs” and constitute a milestone in…