Specific inhibitory neurons in the prefrontal cortex control addiction relapse
Drug addiction carries an extremely high risk of relapse, as cravings can be reignited by minor stimuli even…
FOXJ3 gene identified as the critical link between abnormal brain development and epilepsy
Researchers have discovered that mutations in the FOXJ3 gene act as a “master switch” failure, disrupting how the…
Learning strengthens coordination among sensory neurons in the brain
When you get better at a skill-recognizing a familiar face in a crowd, spotting a typo at a…
Vectorized instructive signals in cortical dendrites
Sacramento, J., Bengio, Y., Costa, R. P. & Senn, W. Dendritic cortical microcircuits approximate the backpropagation algorithm. In…
Study reframes amygdala as the sophisticated learning arbiter
A Dartmouth study challenges the conventional view that the amygdala-the two-sided structure deep in the brain involved in…
Study analyzes alterations in the cerebral cortex in people with psychosis
Researchers at the University of Seville have analyzed alterations in the cerebral cortex in people suffering from psychosis.…
‘Partial reprogramming’ of engram neurons restores memory performance in mice
Age-related memory decline and neurodegenerative diseases like Alzheimer’s are often thought of as irreversible. But the brain is…
Brain immune cells drive persistent negative emotions after repeated binge drinking
New research has identified that neuroinflammation driven by microglia (immune cells in the brain) is a primary underlying…
Prefrontal neural geometry of learned cues guides motivated behaviours
Pearce, J. M. & Bouton, M. E. Theories of associative learning in animals. Annu. Rev. Psychol. 52, 111–139…
Biomimetic brain modeling mirrors animal learning and neural dynamics
A new computational model of the brain based closely on its biology and physiology not only learned a…
Cognitive blocks drive the brain’s advantage over AI
Artificial intelligence may write award-winning essays and diagnose disease with remarkable accuracy, but biological brains still hold the…
Study finds GLP-1 drugs improve strength and reverse aging biology in mice
New multi-omic data reveal that GLP-1 signaling in the brain can drive body-wide rejuvenation, offering a potential weight-neutral…