Lactate and lactylation drive metabolic, epigenetic reprogramming in gynecological cancers
Lactate, once considered a metabolic waste product, is now recognized as a key regulator of cellular homeostasis and…
Dysfunction in chromosome-stabilizing protein identified as a cause of deadly illnesses
New research from the University of Wisconsin–Madison reveals that dysfunction in a protein essential to maintaining stability in…
precision DNA repair may hold clues for human aging
The bowhead whale’s remarkable lifespan and low cancer risk stem from a finely tuned DNA repair system driven…
Hypoxia weakens the body’s infection defense by changing genetic material of neutrophils
Low oxygen levels in the blood can alter the genetic makeup of key immune cells, weakening the body’s…
Eating peanuts while pregnant may influence how a child’s genes respond to breastfeeding
Researchers found that mothers who ate both peanuts and peanut butter during pregnancy had children with distinct DNA…
Frogs help Fred Hutch find the shape of small things
Molecules too few and far between for standard cryo-EM Cryo-EM suspends purified and concentrated molecules in a super…
Ancient DNA uncovers paratyphoid and relapsing fever among Napoleonic troops
Scientists from the Institut Pasteur have genetically analyzed the remains of former soldiers who retreated from Russia in…
Scientists Built Tiny DNA Flowers That Can Move on Their Own and Deliver Targeted Treatments
Visualization of the microscopic “DNA flowers” made by Ronit Freeman in the Freeman Lab at UNC. Credit: Justin…
New gene-editing method can correct many disease-causing mutations in mammalian cells
Some genetic disorders-such as cystic fibrosis, hemophilia and Tay Sachs disease-involve many mutations in a person’s genome, often…
Study forces a textbook rewrite on cell division
Scientists at the Ruđer Bošković Institute (RBI) in Zagreb, Croatia, have discovered that the protein CENP-E, long believed…
Epigenetic editing enables safer and more effective T cell therapies
Arc Institute, Gladstone Institutes, and University of California, San Francisco, scientists have developed an epigenetic editing platform that…
CSIRO voyage discovers new species of shark and crabs off West Australia’s Gascoyne coast
Two thousand feet underwater in the depths of the Gascoyne Marine Park, a dark eel-like creature just 30…