Biologists ‘Resurrect’ 3.2-Billion-Year-Old Enzyme | Sci.News
A team of researchers led by the University of Wisconsin-Madison has reverse-engineered a primordial nitrogen-fixing enzyme, illuminating how…
Sperm RNA aging shift that may explain paternal age effects
A newly revealed “aging cliff” in sperm RNA marks a conserved molecular transition from youth to later life,…
Shingles vaccination is linked to slower biological aging in older adults
Blood-based aging clocks suggest that shingles vaccination may modestly slow molecular aging processes in later life, without clear…
COVID-19 severity is linked to changes in mitochondrial DNA methylation
New evidence from Indian patients shows that severe COVID-19 is associated with distinct mitochondrial methylation signatures and altered…
How “old RNA” reshapes sperm metabolism
Increasing paternal age has been linked to elevated health risks for the next generation, including higher risks of…
Genomic screening uncovers hidden cancer and heart disease risk in young adults
A large Australian pilot shows that testing healthy young adults for high-risk genes can reveal serious disease risk…
Single-cell technique maps pre-malignant gene mutations in solid tissues
A new single-cell profiling technique has mapped pre-malignant gene mutations and their effects in solid tissues for the…
Alternative splicing of DOC2A gene shown to drive schizophrenia risk
In an important new study, Chinese researchers have discovered the previously unrecognized role of alternative splicing of the…
A safer gene-editing tool shows promise for transthyretin amyloidosis treatment
Genetic disorders occur due to alterations in the primary genetic material, deoxyribonucleic acid (DNA), of an organism. Transthyretin…
14,400-Year-Old Woolly Rhinoceros Genome Shows No Evidence of Recent Inbreeding
The woolly rhinoceros (Coelodonta antiquitatis) is a cold-adapted herbivore that went extinct around 14,000 years ago, but little…
DNA analysis of colorectal polyps improves diagnosis and treatment
In about 5–10% of colorectal cancer patients, hereditary factors play a role, with higher percentages among younger patients.…
Key protein in the tuberculosis bacterium helps protect itself from foreign DNA
Researchers at the Indian Institute of Science (IISc), with collaborators from the Institute of Mathematical Sciences (IMSc), have…