New method reveals how human cells initiate DNA replication
When cells proliferate, genomic DNA is precisely duplicated once per cell cycle. Abnormalities in this DNA replication process…
Study reveals ATM kinase as the key driver of replicative senescence
After a finite number of divisions, cells simply give up. As each round of replication trims their telomeres-the…
Epigenetic drift explains why the aging intestine becomes more vulnerable to cancer
Researchers from the Leibniz Institute on Aging – Fritz Lipmann Institute (FLI) in Jena, Germany, the Molecular Biotechnology…
Breakthrough platform reveals the choreography of mammalian transcription
Life’s instructions are written in DNA, but it is the enzyme RNA polymerase II (Pol II) that reads…
These archaea built a distinct genetic code to put pyrrolysine in proteins
 There are few hard and fast rules in the study of life, but perhaps the closest we…
Scientists Want to Snip Your Genes to Fix High Cholesterol Levels
GETTING A DIAGNOSIS of high cholesterol is not fun. It requires a revamp of lifestyle basics like how…
‘Mental model’ approach shown to reduce effects of misinformation about mRNA vaccines
Correcting misinformation after it has gone viral is a common way of informing the public that what they’ve…
Loved in Malaysia, loathed elsewhere: scientists turn bedbugs into crime solvers
Under glaring laboratory lights, a research assistant extends his forearm and carefully inverts a mesh-topped container onto his…
Discovery of sequence-driven DNA methylation offers new path for epigenetic engineering
All the cells in an organism have the exact same genetic sequence. What differs across cell types is…
Intranasal nanomedicine shows promise against glioblastoma
Researchers at Washington University School of Medicine in St. Louis, along with collaborators at Northwestern University, have developed…
CRISPR-edited fungus boosts protein production and cuts environmental impact
In a new study publishing November 19 in the Cell Press journal Trends in Biotechnology, researchers used a…
Subtle changes in the composition of short tandem repeats may shape disease risk
Scientists at The Hospital for Sick Children (SickKids) have revealed a previously overlooked layer of genetic variation that…