A safer gene-editing tool shows promise for transthyretin amyloidosis treatment
Genetic disorders occur due to alterations in the primary genetic material, deoxyribonucleic acid (DNA), of an organism. Transthyretin…
UBC researchers crack code to grow helper t cells from stem cells
For the first time, researchers at the University of British Columbia have demonstrated how to reliably produce an important type…
Vitamin A derivative suppresses immune response and cancer vaccine efficacy
Scientists at the Princeton University Branch of the Ludwig Institute for Cancer Research have identified novel mechanisms by…
Bifunctional biomaterials for postoperative management of osteosarcoma
Background Osteosarcoma is the most prevalent primary malignant bone tumor in children and adolescents. The current standard treatment…
Single-dose dengue vaccine will benefit populations in hard-to-reach regions
 A world-first single-dose vaccine against the dengue virus, manufactured and approved for use in Brazil, will especially…
Tai chi proves as effective as CBT for long-term insomnia relief
A major clinical trial reveals that while tai chi starts slower than CBT, its steady and lasting impact…
Automated EHR system triages cancer symptoms, improves care team efficiency
For many people living with cancer, symptoms such as pain, anxiety or insomnia can quickly spiral into an…
Study compares GLP-1 drug benefits and finds substantial variation in clinical effects
A new umbrella review reveals how GLP-1 therapies shape cardiovascular, renal, and metabolic outcomes in type 2 diabetes…
Understanding leptin’s dual function in MAFLD pathogenesis
Metabolic dysfunction-associated fatty liver disease (MAFLD) has emerged as a predominant chronic liver condition globally, intricately linked with…
Off-label GLP-1 use highlights the cultural pressures driving body anxieties
A new sociomedical perspective shows how off-label use of GLP-1 drugs for slimness is redefining what counts as…
Innovative research reveals FGD3 as a key player in breast cancer cell death
A naturally occurring protein that tends to be expressed at higher levels in breast cancer cells boosts the…
Switching APOE4 to APOE2 in adult mice reduces Alzheimer’s pathology and improves memory
By flipping a single genetic switch from APOE4 to APOE2 in adult mice, researchers reversed key Alzheimer’s-like changes…