Scientists rethink GLP-1 delivery to improve dosing, tolerability, and adherence
From microneedles to nanocarriers, researchers are rethinking how GLP-1 medicines could become longer-lasting, easier to tolerate, and more…
Degrading mutant KRAS protein induces greater lung cancer regression
KRAS is one of the oncogenes most frequently altered in cancer, mutated in approximately one-third of lung adenocarcinomas.…
New cord blood approach boosts survival in blood disease patients
A new way of using umbilical cord blood for treating blood diseases could make the treatment more accessible…
Alzheimer’s monoclonal antibodies fail to deliver meaningful results
Despite successfully removing amyloid plaques from the brain, widely anticipated antibody therapies fail to deliver meaningful cognitive improvements,…
Targeting glutamine metabolism enhances CAR-macrophage cancer therapy
Tumor-associated macrophages (TAMs) within the tumor microenvironment (TME) exhibit significant metabolic dysregulation, which impairs their antitumor function. Specifically,…
Researchers prove magnetic seizures are comparable to ECT in clinical response
A landmark international clinical trial led by researchers at the Centre for Addiction and Mental Health (CAMH) and…
Dutch study shows off-label targeted therapies benefit more cancer patients
The largest published prospective evaluation of off-label targeted cancer therapies has shown that more patients could benefit from…
Nanomedicine offers targeted solutions for breast cancer treatment
Breast cancer (BCA) is one of the most common cancers worldwide, with high mortality and morbidity in women.…
Highly potent opioid shows potential as therapy for pain and opioid use disorder
Researchers at the National Institutes of Health (NIH) have identified a novel, highly potent opioid that shows potential…
Fiber supplement stabilizes blood sugar in gestational diabetes
A simple fiber supplement could reshape the gut microbiome, stabilize blood sugar spikes, and even prevent preterm births…
Blood pressure drug boosts effectiveness of cancer therapy
In a new Dartmouth Cancer Center (DCC) study led by clinical researcher Tyler J. Curiel, MD, MPH, FACP,…
Wholegrain rye changes gut bacteria and lowers inflammation in obesity trial
A 12-week randomized trial found that wholegrain rye did not beat refined wheat for weight loss, but it…