Study uncovers genes and proteins likely to play a causal role in Type 2 diabetes
An international study co-led by researchers from the University of Massachusetts Amherst and Helmholtz Munich in Germany has…
Zebrafish can play a decisive role in clinical interpretation of spinal muscular atrophy
The tiny zebrafish is helping researchers rapidly determine whether a newborn’s genetic mutation is likely to cause spinal…
Genes Tie Gut Motility to Surprising Nutrient: Vitamin B1
Analyzing data from more than 268,000 people, researchers found that genes involved in thiamine (vitamin B1) metabolism play…
Biologists ‘Resurrect’ 3.2-Billion-Year-Old Enzyme | Sci.News
A team of researchers led by the University of Wisconsin-Madison has reverse-engineered a primordial nitrogen-fixing enzyme, illuminating how…
Brain cell precursors show constant myelin-making drive
In experiments with mice, Johns Hopkins Medicine scientists report new evidence that precursors of myelin-producing cells – one…
Sperm RNA aging shift that may explain paternal age effects
A newly revealed “aging cliff” in sperm RNA marks a conserved molecular transition from youth to later life,…
Shingles vaccination is linked to slower biological aging in older adults
Blood-based aging clocks suggest that shingles vaccination may modestly slow molecular aging processes in later life, without clear…
COVID-19 severity is linked to changes in mitochondrial DNA methylation
New evidence from Indian patients shows that severe COVID-19 is associated with distinct mitochondrial methylation signatures and altered…
Single-cell technique maps pre-malignant gene mutations in solid tissues
A new single-cell profiling technique has mapped pre-malignant gene mutations and their effects in solid tissues for the…
Alternative splicing of DOC2A gene shown to drive schizophrenia risk
In an important new study, Chinese researchers have discovered the previously unrecognized role of alternative splicing of the…
Thermogenic beige fat protects blood vessels from hypertension
Obesity causes hypertension. Hypertension causes cardiovascular disease. And cardiovascular disease is the leading cause of death worldwide. While…
A safer gene-editing tool shows promise for transthyretin amyloidosis treatment
Genetic disorders occur due to alterations in the primary genetic material, deoxyribonucleic acid (DNA), of an organism. Transthyretin…