Brain cell precursors show constant myelin-making drive
In experiments with mice, Johns Hopkins Medicine scientists report new evidence that precursors of myelin-producing cells – one…
Sperm RNA aging shift that may explain paternal age effects
A newly revealed “aging cliff” in sperm RNA marks a conserved molecular transition from youth to later life,…
Shingles vaccination is linked to slower biological aging in older adults
Blood-based aging clocks suggest that shingles vaccination may modestly slow molecular aging processes in later life, without clear…
COVID-19 severity is linked to changes in mitochondrial DNA methylation
New evidence from Indian patients shows that severe COVID-19 is associated with distinct mitochondrial methylation signatures and altered…
Single-cell technique maps pre-malignant gene mutations in solid tissues
A new single-cell profiling technique has mapped pre-malignant gene mutations and their effects in solid tissues for the…
Alternative splicing of DOC2A gene shown to drive schizophrenia risk
In an important new study, Chinese researchers have discovered the previously unrecognized role of alternative splicing of the…
Thermogenic beige fat protects blood vessels from hypertension
Obesity causes hypertension. Hypertension causes cardiovascular disease. And cardiovascular disease is the leading cause of death worldwide. While…
A safer gene-editing tool shows promise for transthyretin amyloidosis treatment
Genetic disorders occur due to alterations in the primary genetic material, deoxyribonucleic acid (DNA), of an organism. Transthyretin…
14,400-Year-Old Woolly Rhinoceros Genome Shows No Evidence of Recent Inbreeding
The woolly rhinoceros (Coelodonta antiquitatis) is a cold-adapted herbivore that went extinct around 14,000 years ago, but little…
Fruit fly study identifies genes regulating dopamine and sleep
Dopamine in the brain influences movement, learning, motivation and sleep. In humans, problems with dopamine are linked to…
DNA analysis of colorectal polyps improves diagnosis and treatment
In about 5–10% of colorectal cancer patients, hereditary factors play a role, with higher percentages among younger patients.…
Restoring protein production in motor neuron axons
Researchers at VIB and KU Leuven have identified a molecular process that allows motor neurons to maintain protein…