Over-contracted gut muscles drive gastrointestinal symptoms in myotonic dystrophy
Myotonic dystrophy type 1 (DM1) is the most common form of adult-onset muscular dystrophy, affecting about 1 in…
New findings show why the human intestine uniquely presents gluten to T cells
New evidence shows that human M cells act as fully fledged antigen-presenting cells, processing and presenting gluten peptides…
Study provides new insights into brain signaling during sleep and wakefulness
An international team led by the University of Michigan has introduced new methods that reveal which regions of…
Nanoflower-treated stem cells deliver healthier mitochondria to stressed cells
By engineering nanomaterials that boost mitochondrial biogenesis, researchers show how stem cells can become powerful “mitochondrial biofactories,” offering…
AI-driven method uncovers genetic interactions that fuel cancer progression
University of South Australia scientists have developed a powerful new way to uncover the genetic interactions that fuel…
Small molecule discovery could open the door to new class of treatments for hard-to-treat cancers
Researchers at the UCLA Health Jonsson Comprehensive Cancer Center have identified a small molecule that can inhibit a cancer-driving protein…
Everyday PFAS exposure alters placental function in early pregnancy
By modelling real-world PFAS mixtures found in first-trimester placentas, researchers reveal how everyday chemical exposure can subtly rewire…
Retinal organoids provide a powerful tool to diagnose and study Leber congenital amaurosis
Leber Congenital Amaurosis (LCA) is an inherited retinal disease leading to severe vision impairment from early infancy, affecting…
AI model popEVE: Prioritizing genetic variants effectively
By combining deep evolutionary signals with human population data, the popEVE model provides a novel approach to identifying…
Rice researchers develop resettable serum markers for clearer brain activity signals
Tracking how genes switch on and off in the brain is essential for understanding many neurological diseases, yet…
Gene variant linked to higher risk of chronic rejection after lung transplant
About one third of lung transplant recipients have a genetic variant that makes them more likely to develop…
Discovery of smOOP RNAs reveals hidden rules of cellular phase separation
Inside cells, RNAs and proteins form tiny, liquid-like droplets called biomolecular condensates. These droplets are essential for organizing…