Corneal nerve function declines with age in aniridia patients
Congenital aniridia is a rare disease caused, in most cases, by mutations in the PAX6 gene, which is…
Neanderthal DNA loss tied to ancient interbreeding dynamics
The human genome is a rich, complex record of migration, encounters, and inheritance written over thousands of millennia.…
Researchers reveal why SuperAgers retain youthful brain cell signatures into their 80s
A multiomic atlas of the aging human hippocampus uncovers how epigenetic regulation of neural stem cells and immature…
Research maps lysosomal proteins to study neurodegeneration
Stanford researchers constructed an atlas of the proteins found in the lysosome across different brain cell types, a…
Vitamin B3 shows promise for treating rare genetic disorder
Scientists at Gladstone Institutes have flipped the traditional approach to finding potential treatments for deadly diseases. Instead of…
Simple blood test measuring piRNAs may help better understand health and aging
Research in Aging Cell indicates that blood levels of particular small non-coding RNAs, which regulate gene expression, may…
New Pico C technology maps genome structure before activation
For decades, scientists viewed the genome of a newly fertilised egg as a structural ‘blank slate’ – a…
Study sheds light on behavior of yeast cells in the gut
A new study sheds light on the behavior of yeast cells in the gut, paving the way for…
Neutral polymer enables safer DNA delivery into cells
Researchers from Tokyo Metropolitan University have created a new molecule which carries DNA into biological cells, to treat…
Genetic mismatch identified as major risk factor in cord blood transplantation
A Japanese study of more than 7,400 patients has identified a genetic mismatch that sharply increases the risk…
Gut bacteria patterns help predict insulin resistance in type 2 diabetes, study finds
A new study shows that gut microbiome signatures, analyzed through advanced machine learning, can help identify individuals with…
Researchers identify a genetic brake for the formation of blood vessels in muscles
In an international study, researchers at Lund University in Sweden have identified a gene variant that controls the…