Stanford scientists discover unexpected cancer resistance in aged mice
Old laboratory mice develop substantially fewer and less-aggressive lung tumors than younger animals in a new study led…
Switching APOE4 to APOE2 in adult mice reduces Alzheimer’s pathology and improves memory
By flipping a single genetic switch from APOE4 to APOE2 in adult mice, researchers reversed key Alzheimer’s-like changes…
Study clarifies how biliary atresia overlaps with multiple congenital syndromes
Biliary atresia (BA) represents one of the leading causes of pediatric liver failure, often requiring surgical intervention or…
Researchers Using Neanderthal DNA to Learn More About How Human Faces Develop and Evolve
University of Edinburgh scientist Hannah Long and colleagues show how a region of Neanderthal DNA is better at…
Targeting RNA splicing errors protects against tau-induced neurodegeneration
Alzheimer’s Disease (AD), the leading cause of dementia, affects nearly 40 million individuals globally, resulting in a gradual…
Study uncovers new mechanism for chromosome congression during mitosis
A research team from The University of Osaka, in collaboration with the Massachusetts Institute of Technology, has uncovered…
One-time CRISPR therapy safely lowers cholesterol and triglycerides in early trial
In a 15-patient, Phase 1 one, first-in-human trial, a one-time, CRISPR-Cas9 gene-editing therapy safely reduced LDL cholesterol and…
Multiple protein forms from a single gene offer fresh insight into rare disease mechanisms
Iain Cheeseman and colleagues reveal the underappreciated role of single genes producing multiple proteins in atypical presentations of…
Intensive mind-body retreat rapidly alters brain function and blood biology
Researchers at the University of California San Diego have found that an intensive retreat combining multiple mind-body techniques,…
Alzheimer’s breakthrough reveals how tweaking one gene shields brain connections
Scientists have uncovered a microglial switch that transforms these immune cells from plaque-promoting to plaque-protective, offering a new…
Two main methods for discovering disease genes reveal distinct aspects of biology
The two main approaches for discovering disease genes reveal distinct aspects of biology, a new study shows. While…
Study identifies molecular brake that controls overactive killer T cells
“Why do immune cells that are supposed to eliminate viruses suddenly turn against our own body?” There are…