CRISPR-edited fungus boosts protein production and cuts environmental impact
In a new study publishing November 19 in the Cell Press journal Trends in Biotechnology, researchers used a…
Scientists uncover genetic components linked to bone density in young people
Researchers at Children’s Hospital of Philadelphia (CHOP) revealed important genetic components that affect bone density in children and…
Breast cancer cells use a molecular switch to survive stress
Cells are regularly faced with environmental stresses that may damage or destroy them. To survive, they quickly adjust…
Subtle changes in the composition of short tandem repeats may shape disease risk
Scientists at The Hospital for Sick Children (SickKids) have revealed a previously overlooked layer of genetic variation that…
Innovative research reveals FGD3 as a key player in breast cancer cell death
A naturally occurring protein that tends to be expressed at higher levels in breast cancer cells boosts the…
Stanford scientists discover unexpected cancer resistance in aged mice
Old laboratory mice develop substantially fewer and less-aggressive lung tumors than younger animals in a new study led…
Switching APOE4 to APOE2 in adult mice reduces Alzheimer’s pathology and improves memory
By flipping a single genetic switch from APOE4 to APOE2 in adult mice, researchers reversed key Alzheimer’s-like changes…
Study clarifies how biliary atresia overlaps with multiple congenital syndromes
Biliary atresia (BA) represents one of the leading causes of pediatric liver failure, often requiring surgical intervention or…
Researchers Using Neanderthal DNA to Learn More About How Human Faces Develop and Evolve
University of Edinburgh scientist Hannah Long and colleagues show how a region of Neanderthal DNA is better at…
Targeting RNA splicing errors protects against tau-induced neurodegeneration
Alzheimer’s Disease (AD), the leading cause of dementia, affects nearly 40 million individuals globally, resulting in a gradual…
Study uncovers new mechanism for chromosome congression during mitosis
A research team from The University of Osaka, in collaboration with the Massachusetts Institute of Technology, has uncovered…
One-time CRISPR therapy safely lowers cholesterol and triglycerides in early trial
In a 15-patient, Phase 1 one, first-in-human trial, a one-time, CRISPR-Cas9 gene-editing therapy safely reduced LDL cholesterol and…