Highly protected areas buffer against aridity thresholds in global drylands
Cherlet, M. et al. World Atlas of Desertification (Publication Office of the European Union, 2018). Davies, J. et…
Unravelling the genetics and epigenetics of the ageing tumour microenvironment in cancer
de Magalhaes, J. P. How ageing processes influence cancer. Nat. Rev. Cancer 13, 357–365 (2013). Article PubMed Google…
Mental well-being and work capacity: a cross-sectional study in a sample of the Swedish working population | BMC Public Health
An epidemiological cross-sectional study design was used, and data were collected from autumn 2021 until summer 2022 through…
Sinking carbon sinks | Nature Climate Change
Terrestrial ecosystems take up approximately a third of anthropogenically emitted carbon and are a key component of climate…
Germline genetic variation impacts clonal hematopoiesis landscape and progression to malignancy
Cancer is a genetic disease stemming from a combination of inherited and acquired mutations. Much of our understanding…
Feasibility and clinical utility of expanded genomic newborn screening in the Early Check program
Enrollment rates Between 28 September 2023 and 10 June 2024 (~8.5 months), a total of 2,125 newborns were enrolled.…
Mutational landscape of triple-negative breast cancer in African American women
Patient population Paired tumor and normal samples from 513 self-identified AA women with TNBC were interrogated by WES.…
Systema: a framework for evaluating genetic perturbation response prediction beyond systematic variation
Nonparametric baselines We design two nonparametric baselines that we refer to as perturbed mean and matching mean. Perturbed…
Methods and applications of in vivo CRISPR screening
Auton, A. et al. A global reference for human genetic variation. Nature 526, 68–74 (2015). Article PubMed Google…
Pressure induced superconductivity in hybrid Ruddlesden‒Popper La5Ni3O11 single crystals
Bednorz, J. G. & Müller, K. A. Possible high Tc superconductivity in the Ba–La–Cu–O system. Z. Phys. B:…
Large-scale genome-wide analyses of stuttering
Yairi, E. & Ambrose, N. Epidemiology of stuttering: 21st century advances. J. Fluen. Disord. 38, 66–87 (2013). Google…
The Platinum Pedigree: a long-read benchmark for genetic variants
Gonzaga-Jauregui, C., Lupski, J. R. & Gibbs, R. A. Human genome sequencing in health and disease. Annu. Rev.…