Comprehensive kinase atlas reveals new insights into cell signaling and disease
The enzyme RNA polymerase II transcribes genes into messenger RNA. This process is guided by modifications to the enzyme’s…
Researchers refine tools to map DNA’s 3D structure inside cells
DNA isn’t just a long string of genetic code, but an intricate 3D structure folded inside each cell.…
Inflammation identified as a key driver in the earliest stages of lung cancer
By creating high-resolution cellular and molecular visual maps of lung cancer before and during development, researchers at The…
Two main methods for discovering disease genes reveal distinct aspects of biology
The two main approaches for discovering disease genes reveal distinct aspects of biology, a new study shows. While…
Bowel cancer’s “Big Bang” moment reveals how the disease takes shape
Like the astronomical explosion that kickstarted the universe, bowel cancer has a “Big Bang” moment which determines how…
Study finds high intake of ultra-processed foods tied to reduced DNA methylation
Researchers have found that women who consume more ultra-processed foods exhibit widespread differences in DNA methylation, suggesting early…
Study reveals how “P bodies” heavily influence a cell’s fate
How do stem cells know what to become? Nearly three decades after scientists isolated the first human embryonic…
Large-scale foundation model reconstructs how cells interact within tissues
Researchers at Helmholtz Munich and the Technical University of Munich (TUM) have developed Nicheformer, the first large-scale foundation…
Scientists uncover new obesity genes that reshape understanding of weight and disease risk
A global research team maps how rare and common gene variants jointly drive obesity and metabolic disease, offering…
Massive cross-ancestry study explains why obesity risks differ around the world
By analyzing genetic data from more than 800,000 individuals across six ancestries, researchers have identified previously unknown obesity…
Two microbial metabolites compete to control the cells’ protein building machinery
The microbiome-the trillions of bacteria, viruses, and fungi that live quietly in our body-plays a crucial role in…
Hypoxia weakens the body’s infection defense by changing genetic material of neutrophils
Low oxygen levels in the blood can alter the genetic makeup of key immune cells, weakening the body’s…