Over-contracted gut muscles drive gastrointestinal symptoms in myotonic dystrophy
Myotonic dystrophy type 1 (DM1) is the most common form of adult-onset muscular dystrophy, affecting about 1 in…
New findings show why the human intestine uniquely presents gluten to T cells
New evidence shows that human M cells act as fully fledged antigen-presenting cells, processing and presenting gluten peptides…
AI-driven method uncovers genetic interactions that fuel cancer progression
University of South Australia scientists have developed a powerful new way to uncover the genetic interactions that fuel…
Small molecule discovery could open the door to new class of treatments for hard-to-treat cancers
Researchers at the UCLA Health Jonsson Comprehensive Cancer Center have identified a small molecule that can inhibit a cancer-driving protein…
Everyday PFAS exposure alters placental function in early pregnancy
By modelling real-world PFAS mixtures found in first-trimester placentas, researchers reveal how everyday chemical exposure can subtly rewire…
Retinal organoids provide a powerful tool to diagnose and study Leber congenital amaurosis
Leber Congenital Amaurosis (LCA) is an inherited retinal disease leading to severe vision impairment from early infancy, affecting…
AI model popEVE: Prioritizing genetic variants effectively
By combining deep evolutionary signals with human population data, the popEVE model provides a novel approach to identifying…
Rice researchers develop resettable serum markers for clearer brain activity signals
Tracking how genes switch on and off in the brain is essential for understanding many neurological diseases, yet…
Epigenetic drift explains why the aging intestine becomes more vulnerable to cancer
Researchers from the Leibniz Institute on Aging – Fritz Lipmann Institute (FLI) in Jena, Germany, the Molecular Biotechnology…
Study sheds light on how extracellular vesicles mediate intercellular communication
A new study describes a key molecular mechanism that explains how cells exchange information through extracellular vesicles (EVs),…
Discovery of sequence-driven DNA methylation offers new path for epigenetic engineering
All the cells in an organism have the exact same genetic sequence. What differs across cell types is…
CRISPR-edited fungus boosts protein production and cuts environmental impact
In a new study publishing November 19 in the Cell Press journal Trends in Biotechnology, researchers used a…