New insights into ribosome collisions and stress response
LMU researchers uncover the mechanism by which ribosomes raise alarms in the cell. Ribosomes, the protein factories of…
Development of a polygenic risk score for pelvic organ prolapse in Chinese women
Pelvic organ prolapse (POP), a condition whose development is shaped by both genetic and clinical risk factors, significantly…
Discovery of sequence-driven DNA methylation offers new path for epigenetic engineering
All the cells in an organism have the exact same genetic sequence. What differs across cell types is…
UK Biobank releases the world’s largest metabolomic dataset for disease research
UK Biobank has today [Thursday 20 November] released the final set of data on nearly 250 metabolites – the molecules in our blood produced by…
Scientists uncover genetic components linked to bone density in young people
Researchers at Children’s Hospital of Philadelphia (CHOP) revealed important genetic components that affect bone density in children and…
Parental monitoring can offset genetic risks for conduct problems in adolescents
Parents may have more influence than they realize when it comes to shaping their children’s behavior, especially for…
Neoantigens-loaded DC vaccines show strong potential to overcome tumor resistance
Despite the success of immune checkpoint inhibitors in revolutionizing oncology, their benefits remain limited to a small fraction…
Blood group A linked to a higher risk of primary biliary cholangitis
A major retrospective study shows that people with blood group A face a higher likelihood of autoimmune liver…
Breast cancer cells use a molecular switch to survive stress
Cells are regularly faced with environmental stresses that may damage or destroy them. To survive, they quickly adjust…
Higher autism risk tied to parental postpartum depression
A massive population study reveals that postpartum depression in either parent, especially in both, may signal a substantially…
Johns Hopkins study links mild pancreatic duct dilatation to higher cancer risk
Pancreatic ductal adenocarcinoma is projected to become the second-leading cause of cancer death in the United States by…
Subtle changes in the composition of short tandem repeats may shape disease risk
Scientists at The Hospital for Sick Children (SickKids) have revealed a previously overlooked layer of genetic variation that…