AI model popEVE: Prioritizing genetic variants effectively
By combining deep evolutionary signals with human population data, the popEVE model provides a novel approach to identifying…
New method reveals how human cells initiate DNA replication
When cells proliferate, genomic DNA is precisely duplicated once per cell cycle. Abnormalities in this DNA replication process…
International collaboration develops STREAMS to standardize microbiome data
Microbiomes, the communities of microorganisms that live in and around us, play a vital role in everything from…
New technique helps understand how bacterial shapes contribute to disease
Scientists have long known that bacteria come in many shapes and sizes, but understanding what those differences mean…
Scientists Want to Snip Your Genes to Fix High Cholesterol Levels
GETTING A DIAGNOSIS of high cholesterol is not fun. It requires a revamp of lifestyle basics like how…
Genome-wide association study of delay discounting identifies 11 loci and reveals transdiagnostic associations across mental and physical health
Kirby KN, Petry NM, Bickel WK. Heroin addicts have higher discount rates for delayed rewards than non-drug-using controls.…
Development of a polygenic risk score for pelvic organ prolapse in Chinese women
Pelvic organ prolapse (POP), a condition whose development is shaped by both genetic and clinical risk factors, significantly…
Discovery of sequence-driven DNA methylation offers new path for epigenetic engineering
All the cells in an organism have the exact same genetic sequence. What differs across cell types is…
New clues in pancreas lymph nodes, spleen could help detect and prevent type 1 diabetes
Type 1 diabetes (T1D) impacts nearly two million Americans, and by the time most people learn they have…
Scientists Harness Plants’ Plasticity to Make Key Industrial Chemical
Newswise — UPTON, N.Y. — A team led by scientists at the U.S. Department of Energy’s (DOE) Brookhaven…
Scientists uncover genetic components linked to bone density in young people
Researchers at Children’s Hospital of Philadelphia (CHOP) revealed important genetic components that affect bone density in children and…
Parental monitoring can offset genetic risks for conduct problems in adolescents
Parents may have more influence than they realize when it comes to shaping their children’s behavior, especially for…